| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 4 |
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| Ligand | BDBM50031925 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_3280 (CHEMBL619081) |
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| Ki | 6600±n/a nM |
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| Citation |  Anzini, M; Cappelli, A; Vomero, S; Giorgi, G; Langer, T; Hamon, M; Merahi, N; Emerit, BM; Cagnotto, A; Skorupska, M Novel, potent, and selective 5-HT3 receptor antagonists based on the arylpiperazine skeleton: synthesis, structure, biological activity, and comparative molecular field analysis studies. J Med Chem38:2692-704 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 4 |
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| Name: | 5-hydroxytryptamine receptor 4 |
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| Synonyms: | 5-HT4 | 5-hydroxytryptamine receptor 4 | 5HT4R_CAVPO | HTR4 | Serotonin 4 (5-HT4) receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 43735.29 |
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| Organism: | GUINEA PIG |
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| Description: | 5-HT4 HTR4 GUINEA PIG::O70528 |
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| Residue: | 388 |
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| Sequence: | MDKLDANVSSKEGFGSVEKVVLLTFLSAVILMAILGNLLVMVAVCRDRQLRKIKTNYFIV
SLAFADLLVSVLVMPFGAIELVQDIWVYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYY
AICCQPLVYRNKMTPLRIALMLGGCWVIPMFISFLPIMQGWNNIGIVDLIEKRKFNQNSN
STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHARQIQVLQRAGAPAEGRP
QPADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQLWTAFLWL
GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRD
TVECGGQWESQCHPAASSPLVAAQPIDT
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| BDBM50031925 |
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| n/a |
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| Name | BDBM50031925 |
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| Synonyms: | 6-(4-Methyl-piperazin-1-yl)-7,8-dihydro-benzo[k]phenanthridine | CHEMBL417706 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H23N3 |
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| Mol. Mass. | 329.4381 |
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| SMILES | CN1CCN(CC1)c1nc2ccccc2c-2c1CCc1ccccc-21 |
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| Structure | 
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