| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glyceraldehyde-3-phosphate dehydrogenase |
|---|
| Ligand | BDBM50030961 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_72881 (CHEMBL684049) |
|---|
| IC50 | 6000000±n/a nM |
|---|
| Citation |  Van Calenbergh, S; Verlinde, CL; Soenens, J; De Bruyn, A; Callens, M; Blaton, NM; Peeters, OM; Rozenski, J; Hol, WG; Herdewijn, P Synthesis and structure-activity relationships of analogs of 2'-deoxy-2'-(3-methoxybenzamido)adenosine, a selective inhibitor of trypanosomal glycosomal glyceraldehyde-3-phosphate dehydrogenase. J Med Chem38:3838-49 (1995) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Glyceraldehyde-3-phosphate dehydrogenase |
|---|
| Name: | Glyceraldehyde-3-phosphate dehydrogenase |
|---|
| Synonyms: | G3P_HUMAN | GAPD | GAPDH | Glyceraldehyde-3-phosphate dehydrogenase liver |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 36060.86 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1511315 |
|---|
| Residue: | 335 |
|---|
| Sequence: | MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTV
KAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVI
ISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHA
ITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANV
SVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAG
IALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE
|
|
|
|---|
| BDBM50030961 |
|---|
| n/a |
|---|
| Name | BDBM50030961 |
|---|
| Synonyms: | 2-Methyl-9H-purin-6-ylamine | CHEMBL330897 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C6H7N5 |
|---|
| Mol. Mass. | 149.1533 |
|---|
| SMILES | Cc1nc(N)c2[nH]cnc2n1 |
|---|
| Structure | 
|
|---|
Search and Browse
