| Reaction Details |
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 | Report a problem with these data |
| Target | Melanocyte-stimulating hormone receptor |
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| Ligand | BDBM50115377 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_106826 (CHEMBL717667) |
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| EC50 | 1500±n/a nM |
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| Citation |  Holder, JR; Bauzo, RM; Xiang, Z; Haskell-Luevano, C Structure-activity relationships of the melanocortin tetrapeptide Ac-His-DPhe-Arg-Trp-NH(2) at the mouse melanocortin receptors: part 2 modifications at the Phe position. J Med Chem45:3073-81 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanocyte-stimulating hormone receptor |
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| Name: | Melanocyte-stimulating hormone receptor |
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| Synonyms: | MC1-R | MSHR_MOUSE | Mc1r | Melanocortin receptor 1 | Melanocyte-stimulating hormone receptor | Msh-r |
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| Type: | PROTEIN |
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| Mol. Mass.: | 35238.60 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1498846 |
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| Residue: | 315 |
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| Sequence: | MSTQEPQKSLLGSLNSNATSHLGLATNQSEPWCLYVSIPDGLFLSLGLVSLVENVLVVIA
ITKNRNLHSPMYYFICCLALSDLMVSVSIVLETTIILLLEAGILVARVALVQQLDNLIDV
LICGSMVSSLCFLGIIAIDRYISIFYALRYHSIVTLPRARRAVVGIWMVSIVSSTLFITY
YKHTAVLLCLVTFFLAMLALMAILYAHMFTRACQHAQGIAQLHKRRRSIRQGFCLKGAAT
LTILLGIFFLCWGPFFLHLLLIVLCPQHPTCSCIFKNFNLFLLLIVLSSTVDPLIYAFRS
QELRMTLKEVLLCSW
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| BDBM50115377 |
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| n/a |
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| Name | BDBM50115377 |
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| Synonyms: | 2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-3,3-diphenyl-propionylamino}-5-guanidino-pentanoic acid [1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide | CHEMBL106959 |
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| Type | Small organic molecule |
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| Emp. Form. | C40H47N11O5 |
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| Mol. Mass. | 761.8719 |
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| SMILES | CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |
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| Structure | 
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