| Reaction Details |
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 | Report a problem with these data |
| Target | Melanocortin receptor 4 |
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| Ligand | BDBM50115378 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_104253 (CHEMBL714371) |
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| EC50 | >100000±n/a nM |
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| Citation |  Holder, JR; Bauzo, RM; Xiang, Z; Haskell-Luevano, C Structure-activity relationships of the melanocortin tetrapeptide Ac-His-DPhe-Arg-Trp-NH(2) at the mouse melanocortin receptors: part 2 modifications at the Phe position. J Med Chem45:3073-81 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanocortin receptor 4 |
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| Name: | Melanocortin receptor 4 |
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| Synonyms: | MC4-R | MC4R_MOUSE | Mc4r |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36964.43 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1498850 |
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| Residue: | 332 |
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| Sequence: | MNSTHHHGMYTSLHLWNRSSYGLHGNASESLGKGHPDGGCYEQLFVSPEVFVTLGVISLL
ENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVN
IDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVRRVGIIISCIWAACTVS
GVLFIIYSDSSAVIICLISMFFTMLVLMASLYVHMFLMARLHIKRIAVLPGTGTIRQGTN
MKGAITLTILIGVFVVCWAPFFLHLLFYISCPQNPYCVCFMSHFNLYLILIMCNAVIDPL
IYALRSQELRKTFKEIICFYPLGGICELSSRY
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| BDBM50115378 |
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| n/a |
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| Name | BDBM50115378 |
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| Synonyms: | 2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-2-phenyl-acetylamino}-5-guanidino-pentanoic acid [1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide | CHEMBL318119 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H41N11O5 |
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| Mol. Mass. | 671.7493 |
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| SMILES | CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O)c1ccccc1 |
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| Structure | 
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