| Reaction Details |
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 | Report a problem with these data |
| Target | Acetylcholinesterase |
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| Ligand | BDBM50109572 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_27954 (CHEMBL649134) |
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| Ki | 38800.1±n/a nM |
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| Citation |  Leader, H; Wolfe, AD; Chiang, PK; Gordon, RK Pyridophens: binary pyridostigmine-aprophen prodrugs with differential inhibition of acetylcholinesterase, butyrylcholinesterase, and muscarinic receptors. J Med Chem45:902-10 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Acetylcholinesterase |
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| Name: | Acetylcholinesterase |
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| Synonyms: | ACES_BOVIN | ACHE | Acetylcholinesterase (AChE) | Acetylcholinesterase precursor |
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| Type: | Enzyme |
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| Mol. Mass.: | 67659.62 |
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| Organism: | Bos taurus (bovine) |
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| Description: | n/a |
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| Residue: | 613 |
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| Sequence: | MRPPWCPLHTPSLTPPLLLLLFLIGGGAEAEGPEDPELLVMVRGGRLRGLRLMAPRGPVS
AFLGIPFAEPPVGPRRFLPPEPKRPWPGVLNATAFQSVCYQYVDTLYPGFEGTEMWNPNR
ELSEDCLYLNVWTPYPRPSSPTPVLVWIYGGGFYSGASSLDVYDGRFLTQAEGTVLVSMN
YRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVG
MHLLSPPSRGLFHRAVLQSGAPNGPWATVGVGEARRRATLLARLVGCPPGGAGGNDTELV
ACLRARPAQDLVDHEWRVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGV
VKDEGSYFLVYGAPGFSKDNESLISRAQFLAGVRVGVPQASDLAAEAVVLHYTDWLHPED
PARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYIFEHRASTLSWPLWMGVPHGYE
IEFIFGLPLEPSLNYTIEERTFAQRLMRYWANFARTGDPNDPRDPKAPQWPPYTAGAQQY
VSLNLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQ
FDHYSKQDRCSDL
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| BDBM50109572 |
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| n/a |
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| Name | BDBM50109572 |
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| Synonyms: | 2,2-Diphenyl-propionic acid 3-dimethylcarbamoyloxy-pyridin-2-ylmethyl ester | CHEMBL173955 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H24N2O4 |
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| Mol. Mass. | 404.4584 |
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| SMILES | CN(C)C(=O)Oc1cccnc1COC(=O)C(C)(c1ccccc1)c1ccccc1 |
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| Structure | 
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