| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM50133916 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_62281 (CHEMBL675051) |
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| Ki | 1000±n/a nM |
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| Citation |  Varady, J; Wu, X; Fang, X; Min, J; Hu, Z; Levant, B; Wang, S Molecular modeling of the three-dimensional structure of dopamine 3 (D3) subtype receptor: discovery of novel and potent D3 ligands through a hybrid pharmacophore- and structure-based database searching approach. J Med Chem46:4377-92 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3 |
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| Type: | n/a |
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| Mol. Mass.: | 44243.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 400 |
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| Sequence: | MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
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| BDBM50133916 |
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| n/a |
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| Name | BDBM50133916 |
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| Synonyms: | Benzoic acid 4-isoquinolin-1-yl-1-phenethyl-piperidin-4-yl ester | CHEMBL134526 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H28N2O2 |
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| Mol. Mass. | 436.5448 |
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| SMILES | O=C(OC1(CCN(CCc2ccccc2)CC1)c1nccc2ccccc12)c1ccccc1 |
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| Structure | 
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