| Reaction Details |
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 | Report a problem with these data |
| Target | Transporter |
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| Ligand | BDBM50083536 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_302810 (CHEMBL838518) |
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| Ki | 74500±n/a nM |
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| Citation |  Lomenzo, SA; Rhoden, JB; Izenwasser, S; Wade, D; Kopajtic, T; Katz, JL; Trudell, ML Synthesis and biological evaluation of meperidine analogues at monoamine transporters. J Med Chem48:1336-43 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Transporter |
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| Name: | Transporter |
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| Synonyms: | Monoamine transporters; Norepininephrine & dopamine | Norepinephrine Monoamine transporters |
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| Type: | PROTEIN |
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| Mol. Mass.: | 66787.87 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1463061 |
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| Residue: | 597 |
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| Sequence: | MVTRTRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLF
YMELALGQFNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFASFTLN
LPWTNCGHAWNSPNCTDPKLLNASVLGDHTKYSKYKFTPAAEFYERGVLHLHESSGIHDI
GLPQWQLLLCLMVVIVVLYVSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNG
INAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTIN
CVTSFISGFAIFSILGYMAHEHKVKIEDVATEGAGLVFVLYPEAISTLSGSTFWAVLFFL
MLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTCAVTLGTFLLAMFCITKGGIYVLT
LLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFKPGLYWRLCWKFVSPAFLL
FVVVVSIINFKPLTYDDYVYPPWANWVGWGIALSSMILVPAYVIYKFFSIRGSLWERVAY
GITPENEHHLLALEIELSSLQSFVITSCPIDPLLSSFLFISCQKTLVFKKSGPAPLI
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| BDBM50083536 |
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| n/a |
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| Name | BDBM50083536 |
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| Synonyms: | 4-(3,4-Dichloro-phenyl)-1-methyl-piperidine-4-carboxylic acid ethyl ester | CHEMBL326243 | CHEMBL541124 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H19Cl2NO2 |
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| Mol. Mass. | 316.223 |
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| SMILES | CCOC(=O)C1(CCN(C)CC1)c1ccc(Cl)c(Cl)c1 |
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| Structure | 
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