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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Peroxisome proliferator-activated receptor alpha | ||
| Ligand | BDBM50373906 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_468712 (CHEMBL929848) | ||
| EC50 | 30±n/a nM | ||
| Citation |  Asaki, T; Aoki, T; Hamamoto, T; Sugiyama, Y; Ohmachi, S; Kuwabara, K; Murakami, K; Todo, M Structure-activity studies on 1,3-dioxane-2-carboxylic acid derivatives, a novel class of subtype-selective peroxisome proliferator-activated receptor alpha (PPARalpha) agonists. Bioorg Med Chem16:981-94 (2008) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Peroxisome proliferator-activated receptor alpha | |||
| Name: | Peroxisome proliferator-activated receptor alpha | ||
| Synonyms: | NR1C1 | Nuclear receptor subfamily 1 group C member 1 | PPAR | PPAR alpha/gamma | PPAR-alpha | PPARA | PPARA_HUMAN | Peroxisome Proliferator-Activated Receptor alpha | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor alpha (PPAR alpha) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 52222.08 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q07869 | ||
| Residue: | 468 | ||
| Sequence: |
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| BDBM50373906 | |||
| n/a | |||
| Name | BDBM50373906 | ||
| Synonyms: | CHEMBL272175 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H29NO5 | ||
| Mol. Mass. | 387.4694 | ||
| SMILES | Cc1oc(nc1CCCC[C@H]1CO[C@](C)(OC1)C(O)=O)-c1ccc(C)cc1C |wU:10.10,13.18,wD:13.14,(-2.98,-30.92,;-4.23,-31.82,;-5.7,-31.34,;-6.6,-32.59,;-5.7,-33.83,;-4.23,-33.36,;-2.99,-34.27,;-1.58,-33.64,;-.34,-34.55,;1.07,-33.93,;2.31,-34.83,;3.71,-34.2,;4.96,-35.12,;4.79,-36.65,;5.18,-38.13,;3.38,-37.27,;2.14,-36.36,;6.27,-36.24,;7.36,-37.32,;6.66,-34.76,;-8.14,-32.59,;-8.91,-31.27,;-10.44,-31.26,;-11.22,-32.59,;-12.76,-32.58,;-10.46,-33.92,;-8.92,-33.93,;-8.15,-35.26,)| | ||
| Structure | 
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