| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Isocitrate lyase |
|---|
| Ligand | BDBM50274513 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_537411 (CHEMBL992601) |
|---|
| IC50 | 33800±n/a nM |
|---|
| Citation |  Lee, D; Shin, J; Yoon, KM; Kim, TI; Lee, SH; Lee, HS; Oh, KB Inhibition of Candida albicans isocitrate lyase activity by sesterterpene sulfates from the tropical sponge Dysidea sp. Bioorg Med Chem Lett18:5377-80 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Isocitrate lyase |
|---|
| Name: | Isocitrate lyase |
|---|
| Synonyms: | ACEA_CANAX | ICL1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 61398.95 |
|---|
| Organism: | Candida albicans |
|---|
| Description: | ChEMBL_972063 |
|---|
| Residue: | 550 |
|---|
| Sequence: | MPYTPIDIQKEEADFQKEVAEIKKWWSEPRWRKTKRIYSAEDIAKKRGTLKINHPSSQQA
DKLFKLLETHDADKTVSFTFGALDPIHVAQMAKYLDSIYVSGWQCSSTASTSNEPSPDLA
DYPMDTVPNKVEHLWFAQLFHDRKQREERLTLSKEERAKTPYIDFLRPIIADADTGHGGI
TAIIKLTKMFIERGAAGIHIEDQAPGTKKCGHMAGKVLVPVQEHINRLVAIRASADIFGS
NLLAVARTDSEAATLITSTIDHRDHYFIIGATNPEAGDLAALMAEAESKGIYGNELAAIE
SEWTKKAGLKLFHEAVIDEIKNGNYSNKDALIKKFTDKVNPLSHTSHKEAKKLAKELTGK
DIYFNWDVARAREGYYRYQGGTQCAVMRGRAFAPYADLIWMESALPDYAQAKEFADGVKA
AVPDQWLAYNLSPSFNWNKAMPADEQETYIKRLGKLGYVWQFITLAGLHTTALAVDDFSN
QYSQIGMKAYGQTVQQPEIEKGVEVVKHQKWSGATYIDGLLKMVSGGVTSTAAMGQGVTE
DQFKESKAKA
|
|
|
|---|
| BDBM50274513 |
|---|
| n/a |
|---|
| Name | BDBM50274513 |
|---|
| Synonyms: | CHEMBL483377 | [amino(dimethylamino)methylidene]azanium (2S)-5-(furan-3-yl)-2-{2-[(1S,2R)-1,2,5,5-tetramethyl-1,2,3,4,5,6,7,8-octahydronaphthalen-1-yl]ethyl}pentyl sulfate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H39O5S |
|---|
| Mol. Mass. | 451.64 |
|---|
| SMILES | C[C@@H]1CCC2=C(CCCC2(C)C)[C@@]1(C)CC[C@H](CCCc1ccoc1)COS([O-])(=O)=O |r,t:4| |
|---|
| Structure | 
|
|---|
Search and Browse
