| Reaction Details |
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 | Report a problem with these data |
| Target | Outer membrane protein MIP |
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| Ligand | BDBM50335223 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_701873 (CHEMBL1657165) |
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| IC50 | >100000±n/a nM |
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| Citation |  Juli, C; Sippel, M; Jäger, J; Thiele, A; Weiwad, M; Schweimer, K; Rösch, P; Steinert, M; Sotriffer, CA; Holzgrabe, U Pipecolic acid derivatives as small-molecule inhibitors of the Legionella MIP protein. J Med Chem54:277-83 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Outer membrane protein MIP |
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| Name: | Outer membrane protein MIP |
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| Synonyms: | MIP_LEGPN | Macrophage infectivity potentiator | PPIase | Peptidyl-prolyl cis-trans isomerase | Rotamase | mip |
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| Type: | PROTEIN |
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| Mol. Mass.: | 24869.94 |
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| Organism: | Legionella pneumophila |
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| Description: | ChEMBL_701873 |
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| Residue: | 233 |
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| Sequence: | MKMKLVTAAVMGLAMSTAMAATDATSLATDKDKLSYSIGADLGKNFKNQGIDVNPEAMAK
GMQDAMSGAQLALTEQQMKDVLNKFQKDLMAKRTAEFNKKADENKVKGEAFLTENKNKPG
VVVLPSGLQYKVINAGNGVKPGKSDTVTVEYTGRLIDGTVFDSTEKTGKPATFQVSQVIP
GWTEALQLMPAGSTWEIYVPSGLAYGPRSVGGPIGPNETLIFKIHLISVKKSS
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| BDBM50335223 |
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| n/a |
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| Name | BDBM50335223 |
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| Synonyms: | 3-(3,4,5-trimethoxyphenyl)propyl 1-(3-methyl-2-oxopentanoyl)piperidine-2-carboxylate | CHEMBL1650945 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H35NO7 |
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| Mol. Mass. | 449.5372 |
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| SMILES | CCC(C)C(=O)C(=O)N1CCCCC1C(=O)OCCCc1cc(OC)c(OC)c(OC)c1 |
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| Structure | 
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