| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 6 |
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| Ligand | BDBM50378899 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_718183 (CHEMBL1679229) |
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| IC50 | 32000±n/a nM |
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| Citation |  Bobkova, EV; Liu, WH; Colayco, S; Rascon, J; Vasile, S; Gasior, C; Critton, DA; Chan, X; Dahl, R; Su, Y; Sergienko, E; Chung, TD; Mustelin, T; Page, R; Tautz, L Inhibition of the Hematopoietic Protein Tyrosine Phosphatase by Phenoxyacetic Acids. ACS Med Chem Lett2:113-118 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dual specificity protein phosphatase 6 |
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| Name: | Dual specificity protein phosphatase 6 |
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| Synonyms: | DUS6_HUMAN | DUSP6 | Dual specificity protein phosphatase PYST1 | MAP kinase phosphatase 3 | MKP3 | Mitogen-activated protein kinase phosphatase 3 | PYST1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42305.16 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1476409 |
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| Residue: | 381 |
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| Sequence: | MIDTLRPVPFASEMAISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPG
IMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDTVVLYDESSSDWNENTGGESVLGLLLK
KLKDEGCRAFYLEGGFSKFQAEFSLHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDI
ESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVT
PNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRS
VTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQ
QLYFTTPSNQNVYQVDSLQST
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| BDBM50378899 |
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| n/a |
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| Name | BDBM50378899 |
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| Synonyms: | CHEMBL1672293 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H24N2O6S2 |
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| Mol. Mass. | 524.609 |
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| SMILES | CCOC(=O)C1=C(C)N=c2s\c(=C/c3ccc(OCC(O)=O)cc3)c(=O)n2C1c1ccc(SC)cc1 |c:5,t:8| |
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| Structure | 
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