| Reaction Details |
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 | Report a problem with these data |
| Target | Monoglyceride lipase |
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| Ligand | BDBM50394379 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_854555 (CHEMBL2161050) |
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| IC50 | 102±n/a nM |
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| Citation |  Morera, L; Labar, G; Ortar, G; Lambert, DM Development and characterization of endocannabinoid hydrolases FAAH and MAGL inhibitors bearing a benzotriazol-1-yl carboxamide scaffold. Bioorg Med Chem20:6260-75 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Monoglyceride lipase |
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| Name: | Monoglyceride lipase |
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| Synonyms: | HU-K5 | Lysophospholipase homolog | Lysophospholipase-like | MAGL | MGL | MGLL | MGLL_HUMAN |
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| Type: | Hydrolase |
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| Mol. Mass.: | 33264.56 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human recombinant MGL (Cayman Chemical, cat# 10008354). |
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| Residue: | 303 |
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| Sequence: | MPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEE
LARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLG
HSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPID
SSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADR
LCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHEINMWVSQRTATAGTA
SPP
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| BDBM50394379 |
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| n/a |
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| Name | BDBM50394379 |
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| Synonyms: | CHEMBL2159808 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H24N6O2 |
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| Mol. Mass. | 392.4543 |
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| SMILES | CN(C)C(=O)c1cccc(CN2CCN(CC2)C(=O)n2nnc3ccccc23)c1 |
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| Structure | 
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