| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M2 |
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| Ligand | BDBM50408906 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_139918 (CHEMBL748586) |
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| EC50 | 794.33±n/a nM |
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| Citation |  Botero Cid, HM; Tränkle, C; Baumann, K; Pick, R; Mies-Klomfass, E; Kostenis, E; Mohr, K; Holzgrabe, U Structure-activity relationships in a series of bisquaternary bisphthalimidine derivatives modulating the muscarinic M(2)-receptor allosterically. J Med Chem43:2155-64 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M2 |
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| Name: | Muscarinic acetylcholine receptor M2 |
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| Synonyms: | ACM2_PIG | CHRM2 | Cholinergic, muscarinic | GPM2 | LOC100715343 | Muscarinic acetylcholine receptor M2 | Muscarinic receptor 2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51688.65 |
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| Organism: | GUINEA PIG |
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| Description: | Cholinergic, muscarinic 0 GUINEA PIG::P06199 |
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| Residue: | 466 |
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| Sequence: | MNNSTNSSNSGLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQEPVSPSLVQGRI
VKPNNNNMPGSDEALEHNKIQNGKAPRDAVTENCVQGEEKESSNDSTSVSAVASNMRDDE
ITQDENTVSTSLGHSKDENSKQTCIKIVTKTQKSDSCTPANTTVELVGSSGQNGDEKQNI
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
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| BDBM50408906 |
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| n/a |
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| Name | BDBM50408906 |
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| Synonyms: | CHEMBL303624 |
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| Type | Small organic molecule |
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| Emp. Form. | C44H56N4O2 |
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| Mol. Mass. | 672.9399 |
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| SMILES | C[N+](C)(CCCCCC[N+](C)(C)CCCN1C(c2ccccc2C1=O)c1ccccc1)CCCN1C(c2ccccc2C1=O)c1ccccc1 |
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| Structure | 
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