| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP1 subtype |
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| Ligand | BDBM50423119 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_446786 (CHEMBL897085) |
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| IC50 | 2.5±n/a nM |
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| Citation |  Hall, A; Atkinson, S; Brown, SH; Chessell, IP; Chowdhury, A; Giblin, GM; Goldsmith, P; Healy, MP; Jandu, KS; Johnson, MR; Michel, AD; Naylor, A; Sweeting, JA Discovery of novel, non-acidic 1,5-biaryl pyrrole EP1 receptor antagonists. Bioorg Med Chem Lett17:1200-5 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP1 subtype |
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| Name: | Prostaglandin E2 receptor EP1 subtype |
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| Synonyms: | PE2R1_HUMAN | PGE receptor, EP1 subtype | PTGER1 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP1 subtype | Prostaglandin E2 receptor EP1 subtype (EP1) | Prostanoid EP1 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 41834.57 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34995 |
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| Residue: | 402 |
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| Sequence: | MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQA
AGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFF
GLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYE
LQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRR
PPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLV
GIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLR
QLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF
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| BDBM50423119 |
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| n/a |
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| Name | BDBM50423119 |
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| Synonyms: | CHEMBL232341 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H26N2O4S |
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| Mol. Mass. | 522.614 |
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| SMILES | Cc1ccc(-c2ccccc2OCc2ccccc2)n1-c1cccc(c1)C(=O)NS(=O)(=O)c1ccccc1 |
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| Structure | 
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