Found 621 hits with Last Name = 'chowdhury' and Initial = 'a' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50419411
(CHEMBL1915012)Show InChI InChI=1S/C17H17ClN2O3/c1-9(2)15-7-11-5-13(18)6-12(16(11)23-15)8-20-10(3)4-14(19-20)17(21)22/h4-7,9H,8H2,1-3H3,(H,21,22) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Antagonist activity at human recombinant EP1 receptor expressed in CHO-K1 cells assessed as inhibition of PGE2-mediated intracellular calcium mobiliz... |
Bioorg Med Chem Lett 21: 4343-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.047 BindingDB Entry DOI: 10.7270/Q2RN394N |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50376788
(CHEMBL257997)Show SMILES CC(C)Cc1cn(-c2nc(cs2)C([O-])=O)c2cc(Cl)ccc12 Show InChI InChI=1S/C16H15ClN2O2S/c1-9(2)5-10-7-19(14-6-11(17)3-4-12(10)14)16-18-13(8-22-16)15(20)21/h3-4,6-9H,5H2,1-2H3,(H,20,21)/p-1 | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Antagonist activity against human EP1 receptor expressed in CHOK1 cells assessed as inhibition of PGE2-induced intracellular calcium mobilization by ... |
Bioorg Med Chem Lett 18: 2684-90 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.018 BindingDB Entry DOI: 10.7270/Q2PC338K |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50259611
(CHEMBL467114 | sodium 6-(5-chloro-2-(4-chloro-2-fl...)Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2F)n1 Show InChI InChI=1S/C20H14Cl2FNO3/c21-14-6-7-19(27-11-12-4-5-15(22)10-17(12)23)13(8-14)9-16-2-1-3-18(24-16)20(25)26/h1-8,10H,9,11H2,(H,25,26)/p-1 | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| 7.94 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Antagonist activity at human recombinant EP1 receptor expressed in CHO cells assessed as inhibition of PGE2-mediated intracellular calcium mobilizati... |
Bioorg Med Chem Lett 19: 2599-603 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68 |
More data for this Ligand-Target Pair | |
Thromboxane A2 receptor
(Homo sapiens (Human)) | BDBM50259611
(CHEMBL467114 | sodium 6-(5-chloro-2-(4-chloro-2-fl...)Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2F)n1 Show InChI InChI=1S/C20H14Cl2FNO3/c21-14-6-7-19(27-11-12-4-5-15(22)10-17(12)23)13(8-14)9-16-2-1-3-18(24-16)20(25)26/h1-8,10H,9,11H2,(H,25,26)/p-1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of TP receptor |
Bioorg Med Chem Lett 19: 2599-603 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50259613
(CHEMBL467720 | sodium 6-(5-chloro-2-(2,4-dichlorob...)Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2Cl)n1 Show InChI InChI=1S/C20H14Cl3NO3/c21-14-6-7-19(27-11-12-4-5-15(22)10-17(12)23)13(8-14)9-16-2-1-3-18(24-16)20(25)26/h1-8,10H,9,11H2,(H,25,26)/p-1 | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 25.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Antagonist activity at human recombinant EP1 receptor expressed in CHO cells assessed as inhibition of PGE2-mediated intracellular calcium mobilizati... |
Bioorg Med Chem Lett 19: 2599-603 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50412231
(CHEMBL520438)Show SMILES Cc1cc(nn1Cc1cc(Cl)ccc1OCc1ccccc1)C(=O)Nc1ccc(CO)cc1 Show InChI InChI=1S/C26H24ClN3O3/c1-18-13-24(26(32)28-23-10-7-19(16-31)8-11-23)29-30(18)15-21-14-22(27)9-12-25(21)33-17-20-5-3-2-4-6-20/h2-14,31H,15-17H2,1H3,(H,28,32) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 39.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Antagonist activity of human PGE2 receptor expressed in CHOK1 cells assessed as inhibition of intracellular calcium mobilisation by FLIPR assay |
Bioorg Med Chem Lett 18: 4027-32 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.118 BindingDB Entry DOI: 10.7270/Q2NC62F7 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50412241
(CHEMBL495091)Show SMILES CCN1CCc2ccc(cc2CC1)C(=O)Nc1cc(C)n(Cc2cc(Cl)ccc2OCC(C)C)n1 Show InChI InChI=1S/C28H35ClN4O2/c1-5-32-12-10-21-6-7-23(15-22(21)11-13-32)28(34)30-27-14-20(4)33(31-27)17-24-16-25(29)8-9-26(24)35-18-19(2)3/h6-9,14-16,19H,5,10-13,17-18H2,1-4H3,(H,30,31,34) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 50.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Antagonist activity of human PGE2 receptor expressed in CHOK1 cells assessed as inhibition of intracellular calcium mobilisation by FLIPR assay |
Bioorg Med Chem Lett 18: 4027-32 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.118 BindingDB Entry DOI: 10.7270/Q2NC62F7 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50412224
(CHEMBL479591)Show SMILES Cc1cc(nn1Cc1cc(Cl)ccc1OCc1ccccc1)C(=O)Nc1ccc(CN2CCOCC2)cc1 Show InChI InChI=1S/C30H31ClN4O3/c1-22-17-28(30(36)32-27-10-7-23(8-11-27)19-34-13-15-37-16-14-34)33-35(22)20-25-18-26(31)9-12-29(25)38-21-24-5-3-2-4-6-24/h2-12,17-18H,13-16,19-21H2,1H3,(H,32,36) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 79.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Antagonist activity of human PGE2 receptor expressed in CHOK1 cells assessed as inhibition of intracellular calcium mobilisation by FLIPR assay |
Bioorg Med Chem Lett 18: 4027-32 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.118 BindingDB Entry DOI: 10.7270/Q2NC62F7 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50412232
(CHEMBL523216)Show SMILES CC(C)COc1ccc(Cl)cc1Cn1nc(cc1C)C(=O)Nc1ccc(CN(CCO)CCO)cc1 Show InChI InChI=1S/C27H35ClN4O4/c1-19(2)18-36-26-9-6-23(28)15-22(26)17-32-20(3)14-25(30-32)27(35)29-24-7-4-21(5-8-24)16-31(10-12-33)11-13-34/h4-9,14-15,19,33-34H,10-13,16-18H2,1-3H3,(H,29,35) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 79.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Antagonist activity of human PGE2 receptor expressed in CHOK1 cells assessed as inhibition of intracellular calcium mobilisation by FLIPR assay |
Bioorg Med Chem Lett 18: 4027-32 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.118 BindingDB Entry DOI: 10.7270/Q2NC62F7 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50412239
(CHEMBL492237)Show SMILES CNCc1ccc(NC(=O)c2cc(C)n(Cc3cc(Cl)ccc3OCC(C)C)n2)cc1 Show InChI InChI=1S/C24H29ClN4O2/c1-16(2)15-31-23-10-7-20(25)12-19(23)14-29-17(3)11-22(28-29)24(30)27-21-8-5-18(6-9-21)13-26-4/h5-12,16,26H,13-15H2,1-4H3,(H,27,30) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 79.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Antagonist activity of human PGE2 receptor expressed in CHOK1 cells assessed as inhibition of intracellular calcium mobilisation by FLIPR assay |
Bioorg Med Chem Lett 18: 4027-32 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.118 BindingDB Entry DOI: 10.7270/Q2NC62F7 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50412233
(CHEMBL495107)Show SMILES CC(C)COc1ccc(Cl)cc1Cn1nc(cc1C)C(=O)Nc1ccc(CNCCO)cc1 Show InChI InChI=1S/C25H31ClN4O3/c1-17(2)16-33-24-9-6-21(26)13-20(24)15-30-18(3)12-23(29-30)25(32)28-22-7-4-19(5-8-22)14-27-10-11-31/h4-9,12-13,17,27,31H,10-11,14-16H2,1-3H3,(H,28,32) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Antagonist activity of human PGE2 receptor expressed in CHOK1 cells assessed as inhibition of intracellular calcium mobilisation by FLIPR assay |
Bioorg Med Chem Lett 18: 4027-32 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.118 BindingDB Entry DOI: 10.7270/Q2NC62F7 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50412209
(CHEMBL494466)Show SMILES CC(C)COc1ccc(Cl)cc1Cn1nc(NC(=O)c2ccc(cc2)C2CCCN2)cc1C Show InChI InChI=1S/C26H31ClN4O2/c1-17(2)16-33-24-11-10-22(27)14-21(24)15-31-18(3)13-25(30-31)29-26(32)20-8-6-19(7-9-20)23-5-4-12-28-23/h6-11,13-14,17,23,28H,4-5,12,15-16H2,1-3H3,(H,29,30,32) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Antagonist activity of human PGE2 receptor expressed in CHOK1 cells assessed as inhibition of intracellular calcium mobilisation by FLIPR assay |
Bioorg Med Chem Lett 18: 4027-32 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.118 BindingDB Entry DOI: 10.7270/Q2NC62F7 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50259612
(CHEMBL513491 | sodium 6-(5-chloro-2-(2-chloro-4-fl...)Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(F)cc2Cl)n1 Show InChI InChI=1S/C20H14Cl2FNO3/c21-14-5-7-19(27-11-12-4-6-15(23)10-17(12)22)13(8-14)9-16-2-1-3-18(24-16)20(25)26/h1-8,10H,9,11H2,(H,25,26)/p-1 | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Antagonist activity at human recombinant EP1 receptor expressed in CHO cells assessed as inhibition of PGE2-mediated intracellular calcium mobilizati... |
Bioorg Med Chem Lett 19: 2599-603 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50412225
(CHEMBL480789)Show SMILES CNCc1ccc(NC(=O)c2cc(C)n(Cc3cc(Cl)ccc3OCc3ccccc3)n2)cc1 Show InChI InChI=1S/C27H27ClN4O2/c1-19-14-25(27(33)30-24-11-8-20(9-12-24)16-29-2)31-32(19)17-22-15-23(28)10-13-26(22)34-18-21-6-4-3-5-7-21/h3-15,29H,16-18H2,1-2H3,(H,30,33) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 126 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Antagonist activity of human PGE2 receptor expressed in CHOK1 cells assessed as inhibition of intracellular calcium mobilisation by FLIPR assay |
Bioorg Med Chem Lett 18: 4027-32 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.118 BindingDB Entry DOI: 10.7270/Q2NC62F7 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50412208
(CHEMBL493254)Show SMILES CC(C)COc1ccc(Cl)cc1Cn1nc(NC(=O)c2ccc3CNCCc3c2)cc1C Show InChI InChI=1S/C25H29ClN4O2/c1-16(2)15-32-23-7-6-22(26)12-21(23)14-30-17(3)10-24(29-30)28-25(31)19-4-5-20-13-27-9-8-18(20)11-19/h4-7,10-12,16,27H,8-9,13-15H2,1-3H3,(H,28,29,31) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 126 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Antagonist activity of human PGE2 receptor expressed in CHOK1 cells assessed as inhibition of intracellular calcium mobilisation by FLIPR assay |
Bioorg Med Chem Lett 18: 4027-32 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.118 BindingDB Entry DOI: 10.7270/Q2NC62F7 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50412213
(CHEMBL481689)Show SMILES CC(C)COc1ccc(Cl)cc1Cn1nc(NC(=O)c2ccc(CN3CCCC3)cc2)cc1C Show InChI InChI=1S/C27H33ClN4O2/c1-19(2)18-34-25-11-10-24(28)15-23(25)17-32-20(3)14-26(30-32)29-27(33)22-8-6-21(7-9-22)16-31-12-4-5-13-31/h6-11,14-15,19H,4-5,12-13,16-18H2,1-3H3,(H,29,30,33) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 158 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Antagonist activity of human PGE2 receptor expressed in CHOK1 cells assessed as inhibition of intracellular calcium mobilisation by FLIPR assay |
Bioorg Med Chem Lett 18: 4027-32 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.118 BindingDB Entry DOI: 10.7270/Q2NC62F7 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50412215
(CHEMBL481870)Show SMILES CCNCc1ccc(cc1)C(=O)Nc1cc(C)n(Cc2cc(Cl)ccc2OCC(C)C)n1 Show InChI InChI=1S/C25H31ClN4O2/c1-5-27-14-19-6-8-20(9-7-19)25(31)28-24-12-18(4)30(29-24)15-21-13-22(26)10-11-23(21)32-16-17(2)3/h6-13,17,27H,5,14-16H2,1-4H3,(H,28,29,31) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 158 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Antagonist activity of human PGE2 receptor expressed in CHOK1 cells assessed as inhibition of intracellular calcium mobilisation by FLIPR assay |
Bioorg Med Chem Lett 18: 4027-32 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.118 BindingDB Entry DOI: 10.7270/Q2NC62F7 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50419411
(CHEMBL1915012)Show InChI InChI=1S/C17H17ClN2O3/c1-9(2)15-7-11-5-13(18)6-12(16(11)23-15)8-20-10(3)4-14(19-20)17(21)22/h4-7,9H,8H2,1-3H3,(H,21,22) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Antagonist activity at human recombinant EP3 receptor expressed in CHO-K1 cells assessed as inhibition of PGE2-mediated intracellular calcium mobiliz... |
Bioorg Med Chem Lett 21: 4343-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.047 BindingDB Entry DOI: 10.7270/Q2RN394N |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50414022
(CHEMBL2110364 | GSK-180100B)Show SMILES Cc1cc(nn1Cc1cc(Br)ccc1OCc1ccc(Cl)cc1Cl)C([O-])=O Show InChI InChI=1S/C19H15BrCl2N2O3/c1-11-6-17(19(25)26)23-24(11)9-13-7-14(20)3-5-18(13)27-10-12-2-4-15(21)8-16(12)22/h2-8H,9-10H2,1H3,(H,25,26)/p-1 | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 0.129 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 19: 2599-603 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50422961
(CHEMBL387969)Show SMILES CC(=O)Nc1ccc(cc1C(O)=O)-n1c(C)ccc1-c1cc(Br)ccc1OCc1ccc(F)cc1F Show InChI InChI=1S/C27H21BrF2N2O4/c1-15-3-9-25(32(15)20-7-8-24(31-16(2)33)21(13-20)27(34)35)22-11-18(28)5-10-26(22)36-14-17-4-6-19(29)12-23(17)30/h3-13H,14H2,1-2H3,(H,31,33)(H,34,35) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membrane |
Bioorg Med Chem Lett 17: 916-20 (2007)
Article DOI: 10.1016/j.bmcl.2006.11.059 BindingDB Entry DOI: 10.7270/Q2VX0HV3 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50422978
(CHEMBL228586)Show SMILES COc1ccc(cc1C(O)=O)-n1c(C)ccc1-c1cc(Br)ccc1OCc1ccc(F)cc1F Show InChI InChI=1S/C26H20BrF2NO4/c1-15-3-8-23(30(15)19-7-10-24(33-2)21(13-19)26(31)32)20-11-17(27)5-9-25(20)34-14-16-4-6-18(28)12-22(16)29/h3-13H,14H2,1-2H3,(H,31,32) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membrane |
Bioorg Med Chem Lett 17: 916-20 (2007)
Article DOI: 10.1016/j.bmcl.2006.11.059 BindingDB Entry DOI: 10.7270/Q2VX0HV3 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50423023
(CHEMBL427844)Show SMILES CC(=O)Nc1cc(cc(c1)-n1c(C)ccc1-c1cc(Br)ccc1OCc1ccc(F)cc1F)C(O)=O Show InChI InChI=1S/C27H21BrF2N2O4/c1-15-3-7-25(32(15)22-10-18(27(34)35)9-21(13-22)31-16(2)33)23-11-19(28)5-8-26(23)36-14-17-4-6-20(29)12-24(17)30/h3-13H,14H2,1-2H3,(H,31,33)(H,34,35) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranes |
Bioorg Med Chem Lett 17: 732-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.078 BindingDB Entry DOI: 10.7270/Q2MC91B9 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50423034
(CHEMBL390189)Show SMILES Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1cc(N)cc(c1)C(O)=O Show InChI InChI=1S/C25H19BrF2N2O3/c1-14-2-6-23(30(14)20-9-16(25(31)32)8-19(29)12-20)21-10-17(26)4-7-24(21)33-13-15-3-5-18(27)11-22(15)28/h2-12H,13,29H2,1H3,(H,31,32) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranes |
Bioorg Med Chem Lett 17: 732-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.078 BindingDB Entry DOI: 10.7270/Q2MC91B9 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50422971
(CHEMBL387878)Show SMILES Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1ccc(OC(F)F)c(c1)C(O)=O Show InChI InChI=1S/C26H18BrF4NO4/c1-14-2-7-22(32(14)18-6-9-24(36-26(30)31)20(12-18)25(33)34)19-10-16(27)4-8-23(19)35-13-15-3-5-17(28)11-21(15)29/h2-12,26H,13H2,1H3,(H,33,34) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 0.630 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membrane |
Bioorg Med Chem Lett 17: 916-20 (2007)
Article DOI: 10.1016/j.bmcl.2006.11.059 BindingDB Entry DOI: 10.7270/Q2VX0HV3 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50422986
(CHEMBL228593)Show SMILES Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2)n1-c1cc(N)c(C)c(c1)C(O)=O Show InChI InChI=1S/C26H22BrFN2O3/c1-15-3-9-24(30(15)20-12-21(26(31)32)16(2)23(29)13-20)22-11-18(27)6-10-25(22)33-14-17-4-7-19(28)8-5-17/h3-13H,14,29H2,1-2H3,(H,31,32) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 0.790 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membrane |
Bioorg Med Chem Lett 17: 916-20 (2007)
Article DOI: 10.1016/j.bmcl.2006.11.059 BindingDB Entry DOI: 10.7270/Q2VX0HV3 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50423041
(CHEMBL430360)Show SMILES CC(=O)Nc1cc(cc(c1)-n1c(C)ccc1-c1cc(Br)ccc1OCc1ccc(F)cc1)C(O)=O Show InChI InChI=1S/C27H22BrFN2O4/c1-16-3-9-25(31(16)23-12-19(27(33)34)11-22(14-23)30-17(2)32)24-13-20(28)6-10-26(24)35-15-18-4-7-21(29)8-5-18/h3-14H,15H2,1-2H3,(H,30,32)(H,33,34) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 0.790 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranes |
Bioorg Med Chem Lett 17: 732-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.078 BindingDB Entry DOI: 10.7270/Q2MC91B9 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50422977
(CHEMBL228963)Show SMILES Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cc(C(O)=O)c2cc[nH]c2c1 Show InChI InChI=1S/C27H21ClN2O3/c1-17-7-9-25(30(17)20-14-22(27(31)32)21-11-12-29-24(21)15-20)23-13-19(28)8-10-26(23)33-16-18-5-3-2-4-6-18/h2-15,29H,16H2,1H3,(H,31,32) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membrane |
Bioorg Med Chem Lett 17: 916-20 (2007)
Article DOI: 10.1016/j.bmcl.2006.11.059 BindingDB Entry DOI: 10.7270/Q2VX0HV3 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50422974
(CHEMBL230765)Show SMILES Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2)n1-c1ccc(F)c(c1)C(O)=O Show InChI InChI=1S/C25H18BrF2NO3/c1-15-2-10-23(29(15)19-8-9-22(28)20(13-19)25(30)31)21-12-17(26)5-11-24(21)32-14-16-3-6-18(27)7-4-16/h2-13H,14H2,1H3,(H,30,31) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membrane |
Bioorg Med Chem Lett 17: 916-20 (2007)
Article DOI: 10.1016/j.bmcl.2006.11.059 BindingDB Entry DOI: 10.7270/Q2VX0HV3 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50423033
(CHEMBL428367)Show SMILES Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1cc(cc(c1)C(O)=O)N1CCCCC1=O Show InChI InChI=1S/C30H25BrF2N2O4/c1-18-5-9-27(25-14-21(31)7-10-28(25)39-17-19-6-8-22(32)15-26(19)33)35(18)24-13-20(30(37)38)12-23(16-24)34-11-3-2-4-29(34)36/h5-10,12-16H,2-4,11,17H2,1H3,(H,37,38) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranes |
Bioorg Med Chem Lett 17: 732-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.078 BindingDB Entry DOI: 10.7270/Q2MC91B9 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50422973
(CHEMBL395248)Show SMILES Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1ccc(C)c(c1)C(O)=O Show InChI InChI=1S/C26H20BrF2NO3/c1-15-3-8-20(13-21(15)26(31)32)30-16(2)4-9-24(30)22-11-18(27)6-10-25(22)33-14-17-5-7-19(28)12-23(17)29/h3-13H,14H2,1-2H3,(H,31,32) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membrane |
Bioorg Med Chem Lett 17: 916-20 (2007)
Article DOI: 10.1016/j.bmcl.2006.11.059 BindingDB Entry DOI: 10.7270/Q2VX0HV3 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50423044
(CHEMBL234519)Show SMILES CC(=O)Nc1cc(cc(c1)-n1c(C)ccc1-c1cc(Br)ccc1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C27H23BrN2O4/c1-17-8-10-25(30(17)23-13-20(27(32)33)12-22(15-23)29-18(2)31)24-14-21(28)9-11-26(24)34-16-19-6-4-3-5-7-19/h3-15H,16H2,1-2H3,(H,29,31)(H,32,33) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranes |
Bioorg Med Chem Lett 17: 732-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.078 BindingDB Entry DOI: 10.7270/Q2MC91B9 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50423042
(CHEMBL390238)Show SMILES CN(C(C)=O)c1cc(cc(c1)-n1c(C)ccc1-c1cc(Br)ccc1OCc1ccc(F)cc1F)C(O)=O Show InChI InChI=1S/C28H23BrF2N2O4/c1-16-4-8-26(33(16)23-11-19(28(35)36)10-22(14-23)32(3)17(2)34)24-12-20(29)6-9-27(24)37-15-18-5-7-21(30)13-25(18)31/h4-14H,15H2,1-3H3,(H,35,36) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranes |
Bioorg Med Chem Lett 17: 732-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.078 BindingDB Entry DOI: 10.7270/Q2MC91B9 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50423032
(CHEMBL234727)Show SMILES CC(=O)Nc1cc(cc(c1)-n1c(C)ccc1-c1cc(ccc1OCc1ccccc1)C(F)(F)F)C(O)=O Show InChI InChI=1S/C28H23F3N2O4/c1-17-8-10-25(33(17)23-13-20(27(35)36)12-22(15-23)32-18(2)34)24-14-21(28(29,30)31)9-11-26(24)37-16-19-6-4-3-5-7-19/h3-15H,16H2,1-2H3,(H,32,34)(H,35,36) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranes |
Bioorg Med Chem Lett 17: 732-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.078 BindingDB Entry DOI: 10.7270/Q2MC91B9 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50423026
(CHEMBL234945)Show SMILES Cc1ccc(-c2cc(Cl)ccc2OCc2ccc(F)cc2)n1-c1cc(NS(C)(=O)=O)cc(c1)C(O)=O Show InChI InChI=1S/C26H22ClFN2O5S/c1-16-3-9-24(30(16)22-12-18(26(31)32)11-21(14-22)29-36(2,33)34)23-13-19(27)6-10-25(23)35-15-17-4-7-20(28)8-5-17/h3-14,29H,15H2,1-2H3,(H,31,32) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranes |
Bioorg Med Chem Lett 17: 732-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.078 BindingDB Entry DOI: 10.7270/Q2MC91B9 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50423125
(CHEMBL233768)Show SMILES C[C@@H](NC(=O)c1ccc(cc1)-n1c(C)ccc1-c1cc(Cl)ccc1OCc1ccccc1)c1ccccc1 Show InChI InChI=1S/C33H29ClN2O2/c1-23-13-19-31(30-21-28(34)16-20-32(30)38-22-25-9-5-3-6-10-25)36(23)29-17-14-27(15-18-29)33(37)35-24(2)26-11-7-4-8-12-26/h3-21,24H,22H2,1-2H3,(H,35,37)/t24-/m1/s1 | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 1200-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.12.021 BindingDB Entry DOI: 10.7270/Q2TX3GP8 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50423019
(CHEMBL390038)Show SMILES CC(=O)Nc1cc(cc(c1)-n1c(C)ccc1-c1cc(I)ccc1OCc1ccc(F)cc1F)C(O)=O Show InChI InChI=1S/C27H21F2IN2O4/c1-15-3-7-25(32(15)22-10-18(27(34)35)9-21(13-22)31-16(2)33)23-12-20(30)6-8-26(23)36-14-17-4-5-19(28)11-24(17)29/h3-13H,14H2,1-2H3,(H,31,33)(H,34,35) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranes |
Bioorg Med Chem Lett 17: 732-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.078 BindingDB Entry DOI: 10.7270/Q2MC91B9 |
More data for this Ligand-Target Pair | |
Insulin-like growth factor 1 receptor
(Homo sapiens (Human)) | BDBM50315887
((1s,3s)-3-(8-amino-1-(2-phenylquinolin-7-yl)imidaz...)Show SMILES C[C@@]1(O)C[C@@H](C1)c1nc(-c2ccc3ccc(nc3c2)-c2ccccc2)c2c(N)nccn12 |r,wU:1.1,4.6,wD:1.0,(18.42,-37.26,;17.1,-36.49,;16.31,-37.82,;17.79,-35.11,;16.41,-34.42,;15.72,-35.8,;15.93,-32.97,;16.83,-31.71,;15.91,-30.47,;16.38,-29.01,;15.35,-27.88,;15.81,-26.41,;17.32,-26.08,;17.78,-24.62,;19.27,-24.29,;20.31,-25.42,;19.85,-26.89,;18.35,-27.21,;17.89,-28.68,;21.81,-25.09,;22.85,-26.23,;24.35,-25.9,;24.82,-24.43,;23.77,-23.29,;22.27,-23.63,;14.45,-30.96,;13.11,-30.19,;13.11,-28.65,;11.78,-30.96,;11.78,-32.51,;13.12,-33.28,;14.46,-32.5,)| Show InChI InChI=1S/C26H23N5O/c1-26(32)14-19(15-26)25-30-22(23-24(27)28-11-12-31(23)25)18-8-7-17-9-10-20(29-21(17)13-18)16-5-3-2-4-6-16/h2-13,19,32H,14-15H2,1H3,(H2,27,28)/t19-,26+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Piramal Enterprises Limited
Curated by ChEMBL
| Assay Description Inhibition of IGF1R (unknown origin) using poly-G1 as substrate incubated for 10 mins prior to substrate addition measured after 1 hr by time-resolve... |
Eur J Med Chem 92: 246-56 (2015)
Article DOI: 10.1016/j.ejmech.2014.12.053 BindingDB Entry DOI: 10.7270/Q2639RFV |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50419410
(CHEMBL1915252)Show SMILES Cc1cc(nn1Cc1cc(Cl)cc2cc(oc12)-c1ccccc1)C(O)=O Show InChI InChI=1S/C20H15ClN2O3/c1-12-7-17(20(24)25)22-23(12)11-15-9-16(21)8-14-10-18(26-19(14)15)13-5-3-2-4-6-13/h2-10H,11H2,1H3,(H,24,25) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]GW875240X from human prostanoid EP1 receptor expressed in CHO-K1 cells after 45 mins by topcount liquid scintillation counting |
Bioorg Med Chem Lett 21: 4343-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.047 BindingDB Entry DOI: 10.7270/Q2RN394N |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50423043
(CHEMBL234946)Show SMILES Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1cc(cc(c1)C(O)=O)N1CCCC1=O Show InChI InChI=1S/C29H23BrF2N2O4/c1-17-4-8-26(24-13-20(30)6-9-27(24)38-16-18-5-7-21(31)14-25(18)32)34(17)23-12-19(29(36)37)11-22(15-23)33-10-2-3-28(33)35/h4-9,11-15H,2-3,10,16H2,1H3,(H,36,37) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranes |
Bioorg Med Chem Lett 17: 732-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.078 BindingDB Entry DOI: 10.7270/Q2MC91B9 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50423037
(CHEMBL234518)Show SMILES CC(=O)Nc1cc(cc(c1)-n1c(C)ccc1-c1cc(Cl)ccc1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C27H23ClN2O4/c1-17-8-10-25(30(17)23-13-20(27(32)33)12-22(15-23)29-18(2)31)24-14-21(28)9-11-26(24)34-16-19-6-4-3-5-7-19/h3-15H,16H2,1-2H3,(H,29,31)(H,32,33) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranes |
Bioorg Med Chem Lett 17: 732-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.078 BindingDB Entry DOI: 10.7270/Q2MC91B9 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50422983
(CHEMBL395488)Show SMILES Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1ccc(O)c(c1)C(O)=O Show InChI InChI=1S/C25H18BrF2NO4/c1-14-2-7-22(29(14)18-6-8-23(30)20(12-18)25(31)32)19-10-16(26)4-9-24(19)33-13-15-3-5-17(27)11-21(15)28/h2-12,30H,13H2,1H3,(H,31,32) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membrane |
Bioorg Med Chem Lett 17: 916-20 (2007)
Article DOI: 10.1016/j.bmcl.2006.11.059 BindingDB Entry DOI: 10.7270/Q2VX0HV3 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50422981
(CHEMBL230766)Show SMILES Cc1ccc(-c2cc(ccc2OCc2ccccc2)C(F)(F)F)n1-c1ccc(F)c(c1)C(O)=O Show InChI InChI=1S/C26H19F4NO3/c1-16-7-11-23(31(16)19-9-10-22(27)20(14-19)25(32)33)21-13-18(26(28,29)30)8-12-24(21)34-15-17-5-3-2-4-6-17/h2-14H,15H2,1H3,(H,32,33) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membrane |
Bioorg Med Chem Lett 17: 916-20 (2007)
Article DOI: 10.1016/j.bmcl.2006.11.059 BindingDB Entry DOI: 10.7270/Q2VX0HV3 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50422967
(CHEMBL426913)Show SMILES Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cc(N)c(C)c(c1)C(O)=O Show InChI InChI=1S/C26H23ClN2O3/c1-16-8-10-24(29(16)20-13-21(26(30)31)17(2)23(28)14-20)22-12-19(27)9-11-25(22)32-15-18-6-4-3-5-7-18/h3-14H,15,28H2,1-2H3,(H,30,31) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membrane |
Bioorg Med Chem Lett 17: 916-20 (2007)
Article DOI: 10.1016/j.bmcl.2006.11.059 BindingDB Entry DOI: 10.7270/Q2VX0HV3 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50422963
(CHEMBL228638)Show SMILES Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2)n1-c1ccc(OC(F)F)c(c1)C(O)=O Show InChI InChI=1S/C26H19BrF3NO4/c1-15-2-9-22(31(15)19-8-11-24(35-26(29)30)21(13-19)25(32)33)20-12-17(27)5-10-23(20)34-14-16-3-6-18(28)7-4-16/h2-13,26H,14H2,1H3,(H,32,33) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membrane |
Bioorg Med Chem Lett 17: 916-20 (2007)
Article DOI: 10.1016/j.bmcl.2006.11.059 BindingDB Entry DOI: 10.7270/Q2VX0HV3 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50423128
(CHEMBL232117)Show SMILES Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1ccc(cc1)C(=O)NCc1ccccn1 Show InChI InChI=1S/C31H26ClN3O2/c1-22-10-16-29(28-19-25(32)13-17-30(28)37-21-23-7-3-2-4-8-23)35(22)27-14-11-24(12-15-27)31(36)34-20-26-9-5-6-18-33-26/h2-19H,20-21H2,1H3,(H,34,36) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 1200-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.12.021 BindingDB Entry DOI: 10.7270/Q2TX3GP8 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50423154
(CHEMBL232340)Show SMILES Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cccc(c1)C(=O)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C31H25ClN2O4S/c1-22-15-17-29(28-20-25(32)16-18-30(28)38-21-23-9-4-2-5-10-23)34(22)26-12-8-11-24(19-26)31(35)33-39(36,37)27-13-6-3-7-14-27/h2-20H,21H2,1H3,(H,33,35) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 17: 1200-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.12.021 BindingDB Entry DOI: 10.7270/Q2TX3GP8 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50423018
(CHEMBL390190)Show SMILES CC(=O)Nc1cc(cc(c1)-n1c(C)ccc1-c1cc(Cl)ccc1OCc1ccc(F)cc1)C(O)=O Show InChI InChI=1S/C27H22ClFN2O4/c1-16-3-9-25(31(16)23-12-19(27(33)34)11-22(14-23)30-17(2)32)24-13-20(28)6-10-26(24)35-15-18-4-7-21(29)8-5-18/h3-14H,15H2,1-2H3,(H,30,32)(H,33,34) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranes |
Bioorg Med Chem Lett 17: 732-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.078 BindingDB Entry DOI: 10.7270/Q2MC91B9 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50422964
(CHEMBL414978)Show SMILES Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1cc(C(O)=O)c2ccccc2c1 Show InChI InChI=1S/C29H20BrF2NO3/c1-17-6-10-27(33(17)22-12-18-4-2-3-5-23(18)24(15-22)29(34)35)25-13-20(30)8-11-28(25)36-16-19-7-9-21(31)14-26(19)32/h2-15H,16H2,1H3,(H,34,35) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membrane |
Bioorg Med Chem Lett 17: 916-20 (2007)
Article DOI: 10.1016/j.bmcl.2006.11.059 BindingDB Entry DOI: 10.7270/Q2VX0HV3 |
More data for this Ligand-Target Pair | |
Thromboxane A2 receptor
(Homo sapiens (Human)) | BDBM50423023
(CHEMBL427844)Show SMILES CC(=O)Nc1cc(cc(c1)-n1c(C)ccc1-c1cc(Br)ccc1OCc1ccc(F)cc1F)C(O)=O Show InChI InChI=1S/C27H21BrF2N2O4/c1-15-3-7-25(32(15)22-10-18(27(34)35)9-21(13-22)31-16(2)33)23-11-19(28)5-8-26(23)36-14-17-4-6-20(29)12-24(17)30/h3-13H,14H2,1-2H3,(H,31,33)(H,34,35) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of TP receptor |
Bioorg Med Chem Lett 17: 732-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.078 BindingDB Entry DOI: 10.7270/Q2MC91B9 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50422972
(CHEMBL397655)Show SMILES Cc1ccc(-c2cc(Cl)ccc2OCc2ccc(F)cc2F)n1-c1ccc(C)c(c1)C(O)=O Show InChI InChI=1S/C26H20ClF2NO3/c1-15-3-8-20(13-21(15)26(31)32)30-16(2)4-9-24(30)22-11-18(27)6-10-25(22)33-14-17-5-7-19(28)12-23(17)29/h3-13H,14H2,1-2H3,(H,31,32) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membrane |
Bioorg Med Chem Lett 17: 916-20 (2007)
Article DOI: 10.1016/j.bmcl.2006.11.059 BindingDB Entry DOI: 10.7270/Q2VX0HV3 |
More data for this Ligand-Target Pair | |