| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP1 subtype |
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| Ligand | BDBM50419411 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_785480 (CHEMBL1919959) |
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| Ki | 0.398±n/a nM |
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| Citation |  Allan, AC; Billinton, A; Brown, SH; Chowdhury, A; Eatherton, AJ; Fieldhouse, C; Giblin, GM; Goldsmith, P; Hall, A; Hurst, DN; Naylor, A; Rawlings, DA; Sime, M; Scoccitti, T; Theobald, PJ Discovery of a novel series of nonacidic benzofuran EP1 receptor antagonists. Bioorg Med Chem Lett21:4343-8 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP1 subtype |
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| Name: | Prostaglandin E2 receptor EP1 subtype |
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| Synonyms: | PE2R1_HUMAN | PGE receptor, EP1 subtype | PTGER1 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP1 subtype | Prostaglandin E2 receptor EP1 subtype (EP1) | Prostanoid EP1 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 41834.57 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34995 |
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| Residue: | 402 |
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| Sequence: | MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQA
AGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFF
GLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYE
LQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRR
PPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLV
GIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLR
QLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF
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| BDBM50419411 |
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| n/a |
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| Name | BDBM50419411 |
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| Synonyms: | CHEMBL1915012 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H17ClN2O3 |
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| Mol. Mass. | 332.781 |
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| SMILES | CC(C)c1cc2cc(Cl)cc(Cn3nc(cc3C)C(O)=O)c2o1 |
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| Structure | 
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