BDBM50423023 CHEMBL427844

SMILES: CC(=O)Nc1cc(cc(c1)-n1c(C)ccc1-c1cc(Br)ccc1OCc1ccc(F)cc1F)C(O)=O

InChI Key: InChIKey=YWMJHCFRFHOSCO-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50423023   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP1 subtype (EP1) (Homo sapiens (Human))	BDBM50423023 (CHEMBL427844) Show SMILES CC(=O)Nc1cc(cc(c1)-n1c(C)ccc1-c1cc(Br)ccc1OCc1ccc(F)cc1F)C(O)=O Show InChI InChI=1S/C27H21BrF2N2O4/c1-15-3-7-25(32(15)22-10-18(27(34)35)9-21(13-22)31-16(2)33)23-11-19(28)5-8-26(23)36-14-17-4-6-20(29)12-24(17)30/h3-13H,14H2,1-2H3,(H,31,33)(H,34,35)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 17: 732-5 (2007) Article DOI: 10.1016/j.bmcl.2006.10.078 BindingDB Entry DOI: 10.7270/Q2MC91B9
					More data for this Ligand-Target Pair
Prostanoid TP receptor (Homo sapiens (Human))	BDBM50423023 (CHEMBL427844) Show SMILES CC(=O)Nc1cc(cc(c1)-n1c(C)ccc1-c1cc(Br)ccc1OCc1ccc(F)cc1F)C(O)=O Show InChI InChI=1S/C27H21BrF2N2O4/c1-15-3-7-25(32(15)22-10-18(27(34)35)9-21(13-22)31-16(2)33)23-11-19(28)5-8-26(23)36-14-17-4-6-20(29)12-24(17)30/h3-13H,14H2,1-2H3,(H,31,33)(H,34,35)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of TP receptor				Bioorg Med Chem Lett 17: 732-5 (2007) Article DOI: 10.1016/j.bmcl.2006.10.078 BindingDB Entry DOI: 10.7270/Q2MC91B9
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50423023 (CHEMBL427844) Show SMILES CC(=O)Nc1cc(cc(c1)-n1c(C)ccc1-c1cc(Br)ccc1OCc1ccc(F)cc1F)C(O)=O Show InChI InChI=1S/C27H21BrF2N2O4/c1-15-3-7-25(32(15)22-10-18(27(34)35)9-21(13-22)31-16(2)33)23-11-19(28)5-8-26(23)36-14-17-4-6-20(29)12-24(17)30/h3-13H,14H2,1-2H3,(H,31,33)(H,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of EP4 receptor				Bioorg Med Chem Lett 17: 732-5 (2007) Article DOI: 10.1016/j.bmcl.2006.10.078 BindingDB Entry DOI: 10.7270/Q2MC91B9
					More data for this Ligand-Target Pair