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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Similar to alpha-tubulin isoform 1 | ||
| Ligand | BDBM50055043 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1454846 (CHEMBL3363845) | ||
| IC50 | >400000±n/a nM | ||
| Citation |  Porců, E; Sipos, A; Basso, G; Hamel, E; Bai, R; Stempfer, V; Udvardy, A; Bényei, AC; Schmidhammer, H; Antus, S; Viola, G Novel 9'-substituted-noscapines: synthesis with Suzuki cross-coupling, structure elucidation and biological evaluation. Eur J Med Chem84:476-90 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Similar to alpha-tubulin isoform 1 | |||
| Name: | Similar to alpha-tubulin isoform 1 | ||
| Synonyms: | Similar to alpha-tubulin isoform 1 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 10383.05 | ||
| Organism: | Bos taurus | ||
| Description: | ChEMBL_104716 | ||
| Residue: | 99 | ||
| Sequence: |
| ||
| BDBM50055043 | |||
| n/a | |||
| Name | BDBM50055043 | ||
| Synonyms: | CHEMBL3323244 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C29H29NO8 | ||
| Mol. Mass. | 519.5425 | ||
| SMILES | [H][C@@]1(OC(=O)c2c1ccc(OC)c2OC)[C@]1([H])N(C)CCc2c(c3OCOc3c(OC)c12)-c1ccccc1OC |r,wD:15.17,1.0,(20.04,-28.64,;21.39,-29.41,;22.64,-30.31,;22.16,-31.78,;23.07,-33.02,;20.62,-31.78,;20.15,-30.32,;18.65,-30.01,;17.62,-31.15,;18.11,-32.61,;17.08,-33.76,;15.58,-33.45,;19.61,-32.92,;20.09,-34.38,;19.06,-35.53,;21.38,-27.87,;22.7,-28.63,;22.72,-27.09,;24.06,-27.85,;22.72,-25.53,;21.37,-24.76,;20.03,-25.54,;18.69,-24.78,;17.37,-25.55,;15.89,-25.07,;14.98,-26.32,;15.89,-27.57,;17.36,-27.09,;18.7,-27.86,;18.69,-29.4,;17.36,-30.17,;20.04,-27.1,;18.69,-23.24,;20.02,-22.47,;20.02,-20.94,;18.68,-20.17,;17.35,-20.95,;17.35,-22.48,;16.03,-23.26,;14.69,-22.5,)| | ||
| Structure | 
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