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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | CREB-binding protein | ||
| Ligand | BDBM50172112 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1579123 (CHEMBL3811651) | ||
| Kd | 6200±n/a nM | ||
| Citation |  Unzue, A; Zhao, H; Lolli, G; Dong, J; Zhu, J; Zechner, M; Dolbois, A; Caflisch, A; Nevado, C The"Gatekeeper" Residue Influences the Mode of Binding of Acetyl Indoles to Bromodomains. J Med Chem59:3087-97 (2016) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| CREB-binding protein | |||
| Name: | CREB-binding protein | ||
| Synonyms: | CBP | CBP_HUMAN | CREB-binding protein (CBP) | CREB-binding protein (CREBBP) | CREBBP | ||
| Type: | Transcription Coactivator | ||
| Mol. Mass.: | 265411.66 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q92793 | ||
| Residue: | 2442 | ||
| Sequence: |
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| BDBM50172112 | |||
| n/a | |||
| Name | BDBM50172112 | ||
| Synonyms: | CHEMBL3809834 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C16H15N3O2 | ||
| Mol. Mass. | 281.3092 | ||
| SMILES | CC(=O)n1cc(-c2c(C)nn3CCOc23)c2ccccc12 |(1.43,-3.63,;2.25,-2.7,;3.46,-2.95,;1.77,-1.24,;2.67,.02,;1.77,1.24,;2.24,2.71,;3.72,3.06,;4.66,2.25,;3.84,4.61,;2.39,5.19,;1.61,6.51,;.09,6.12,;0,4.59,;1.42,4.01,;.3,.77,;-1.03,1.56,;-2.39,.77,;-2.39,-.77,;-1.03,-1.56,;.3,-.77,)| | ||
| Structure | 
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