| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histamine H3 receptor |
|---|
| Ligand | BDBM50215540 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_83627 |
|---|
| Ki | 1862±n/a nM |
|---|
| Citation |  Tozer, MJ; Harper, EA; Kalindjian, SB; Pether, MJ; Shankley, NP; Watt, GF From histamine to imidazolylalkyl-sulfonamides: the design of a novel series of histamine H3-receptor antagonists. Bioorg Med Chem Lett9:1825-30 (1999) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Histamine H3 receptor |
|---|
| Name: | Histamine H3 receptor |
|---|
| Synonyms: | HISTAMINE H3 | HRH3 | HRH3_CAVPO | Histamine H3 receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 48753.61 |
|---|
| Organism: | GUINEA PIG |
|---|
| Description: | HISTAMINE H3 HRH3 GUINEA PIG::Q9JI35 |
|---|
| Residue: | 445 |
|---|
| Sequence: | MERAPPDGLMNASGALAGEAAAAAGGARTFSAAWTAVLAALMALLIVATVLGNALVMLAF
VADSSLRTQNNFFLLNLAISDFLVGVFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCT
SSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMVLVWVLAFLLYGPAILSWEYLSG
GSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGARE
AGPDPLPEAQSSPPQPPPGCWGCWPKGQGESMPLHRYGVGEAGPGAEAGEAALGGGSGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHSSLEHCWK
|
|
|
|---|
| BDBM50215540 |
|---|
| n/a |
|---|
| Name | BDBM50215540 |
|---|
| Synonyms: | CHEMBL53056 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H15N3O2S |
|---|
| Mol. Mass. | 265.331 |
|---|
| SMILES | O=S(=O)(Cc1ccccc1)NCCc1c[nH]cn1 |
|---|
| Structure | 
|
|---|
Search and Browse
