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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Prostaglandin G/H synthase 2 | ||
| Ligand | BDBM50422583 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_157825 (CHEMBL769429) | ||
| IC50 | 3750±n/a nM | ||
| Citation |  Hyup, YH; Kwan, JK; Kang, SH; Noh, MS; Ha, JY; Kyu, JK; Min, KM; Hoon, CH; Chung, S 2,3-Diarylbenzopyran derivatives as a novel class of selective cyclooxygenase-2 inhibitors. Bioorg Med Chem Lett13:413-7 (2003) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Prostaglandin G/H synthase 2 | |||
| Name: | Prostaglandin G/H synthase 2 | ||
| Synonyms: | Cox-2 | Cox2 | Cyclooxygenase-2 | Cyclooxygenase-2 (COX-2) | Glucocorticoid-regulated inflammatory cyclooxygenase | Gripghs | Macrophage activation-associated marker protein P71/73 | PES-2 | PGH synthase 2 | PGH2_MOUSE | PGHS-2 | PHS II | Pghs-b | Prostaglandin G/H synthase (cyclooxygenase) | Prostaglandin H2 synthase 2 | Prostaglandin-endoperoxide synthase 2 | Ptgs2 | TIS10 protein | Tis10 | ||
| Type: | Protein | ||
| Mol. Mass.: | 69020.39 | ||
| Organism: | Mus musculus (Mouse) | ||
| Description: | Q05769 | ||
| Residue: | 604 | ||
| Sequence: |
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| BDBM50422583 | |||
| n/a | |||
| Name | BDBM50422583 | ||
| Synonyms: | CHEMBL134774 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C26H18O4S | ||
| Mol. Mass. | 426.484 | ||
| SMILES | CS(=O)(=O)c1ccc(cc1)-c1oc2ccccc2c(=O)c1-c1cccc2ccccc12 |(12.3,-6.58,;10.94,-5.8,;11.72,-4.44,;10.16,-7.15,;9.59,-5.01,;9.59,-3.47,;8.24,-2.7,;6.91,-3.47,;6.91,-5.01,;8.24,-5.78,;5.57,-2.7,;4.22,-3.47,;2.9,-2.7,;1.57,-3.47,;.22,-2.7,;.22,-1.15,;1.57,-.38,;2.9,-1.15,;4.22,-.38,;4.22,1.16,;5.57,-1.15,;6.91,-.38,;8.24,-1.15,;9.57,-.38,;9.57,1.16,;8.23,1.92,;8.21,3.45,;6.9,4.22,;5.56,3.44,;5.57,1.91,;6.91,1.16,)| | ||
| Structure | 
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