Ki Summary

Reaction Details

Report a problem with these data

Target

Probable G-protein coupled receptor 34

Ligand

BDBM50238938

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_1664555 (CHEMBL4014236)

EC50

14±n/a nM

Citation

Sayama, M; Sayama, M; Sayama, M; Inoue, A; Inoue, A; Inoue, A; Nakamura, S; Nakamura, S; Nakamura, S; Jung, S; Jung, S; Jung, S; Ikubo, M; Ikubo, M; Ikubo, M; Otani, Y; Otani, Y; Otani, Y; Uwamizu, A; Uwamizu, A; Uwamizu, A; Kishi, T; Kishi, T; Kishi, T; Makide, K; Makide, K; Makide, K; Aoki, J; Aoki, J; Aoki, J; Hirokawa, T; Hirokawa, T; Hirokawa, T; Ohwada, T; Ohwada, T; Ohwada, T Probing the Hydrophobic Binding Pocket of G-Protein-Coupled Lysophosphatidylserine Receptor GPR34/LPS J Med Chem60:6384-6399 (2017) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

Probable G-protein coupled receptor 34

Name:

Probable G-protein coupled receptor 34

Synonyms:

G protein-coupled receptor 34 | GPR34_MOUSE | Gpr34 | Probable G-protein coupled receptor 34

Type:

PROTEIN

Mol. Mass.:

43201.40

Organism:

Mus musculus

Description:

ChEMBL_102842

Residue:

375

Sequence:

MTTTSVDSWLCSSHGMHFITNYSDQASQNFSGVPNVTSCPMDEKLLSTVLTTFYSVIFLV
GLVGNIIALYVFLGIHRKRNSIQIYLLNVAVADLLLIFCLPFRIMYHINQNKWTLGVILC
KVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRRAITTKQSIYVCCIVWTVALAGFL
TMIILTLKKGGHNSTMCFHYRDRHNAKGEAIFNFVLVVMFWLIFLLIILSYIKIGKNLLR
ISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAFRFIYISSQLNVSSCYWKEIIHK
TNEIMLVFSSFNSCLDPVMYFLMSSNIRKIMCQLLFRRFQSEASRSESTSEFKPGHSLHD
LSVTVKMPQYSTKGN

BDBM50238938

n/a

Name

BDBM50238938

Synonyms:

CHEMBL4095241

Type

Small organic molecule

Emp. Form.

C38H44NO10P

Mol. Mass.

705.7304

SMILES

CC(C)(C)c1cccc(c1)-c1ccc(Oc2cccc(COc3ccccc3CCC(=O)OCCCOP(O)(=O)OC[C@H](N)C(O)=O)c2)cc1 |r|

Structure