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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Corticotropin-releasing factor-binding protein | ||
| Ligand | BDBM40650 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex | ||
| EC50 | >53000±n/a nM | ||
| Citation |  PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay(2012)[AID] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Corticotropin-releasing factor-binding protein | |||
| Name: | Corticotropin-releasing factor-binding protein | ||
| Synonyms: | CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 36143.95 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P24387 | ||
| Residue: | 322 | ||
| Sequence: |
| ||
| BDBM40650 | |||
| n/a | |||
| Name | BDBM40650 | ||
| Synonyms: | 11-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-3,3,7,8-tetramethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one | 6-(1,5-dimethyl-3-oxidanylidene-2-phenyl-pyrazol-4-yl)-2,3,9,9-tetramethyl-6,8,10,11-tetrahydro-5H-benzo[b][1,4]benzodiazepin-7-one | 6-(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)-2,3,9,9-tetramethyl-6,8,10,11-tetrahydro-5H-benzo[b][1,4]benzodiazepin-7-one | 6-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-2,3,9,9-tetramethyl-6,8,10,11-tetrahydro-5H-benzo[b][1,4]benzodiazepin-7-one | 6-(3-keto-1,5-dimethyl-2-phenyl-3-pyrazolin-4-yl)-2,3,9,9-tetramethyl-6,8,10,11-tetrahydro-5H-benzo[b][1,4]benzodiazepin-7-one | MLS000097259 | SMR000075783 | cid_2951463 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C28H32N4O2 | ||
| Mol. Mass. | 456.5793 | ||
| SMILES | Cc1c(C2Nc3cc(C)c(C)cc3N=C3CC(C)(C)CC(=O)C23)c(=O)n(-c2ccccc2)n1C |t:14| | ||
| Structure | 
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