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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fibroblast growth factor receptor 3 | ||
| Ligand | BDBM102521 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | LanthaScreen TR-FRET Assay | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 605±n/a nM | ||
| Comments | extracted | ||
| Citation |  Furet, P; Graus Porta, D; Guagnano, V Quinoline carboxamide derivatives as protein tyrosine kinase inhibitors US Patent US8815901 Publication Date 8/26/2014 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fibroblast growth factor receptor 3 | |||
| Name: | Fibroblast growth factor receptor 3 | ||
| Synonyms: | CD_antigen: CD333 | FGFR-3 | FGFR3 | FGFR3_HUMAN | Fibroblast growth factor receptor | Fibroblast growth factor receptor 3 (FGFR3) | JTK4 | ||
| Type: | Protein | ||
| Mol. Mass.: | 87699.57 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P22607 | ||
| Residue: | 806 | ||
| Sequence: |
| ||
| BDBM102521 | |||
| n/a | |||
| Name | BDBM102521 | ||
| Synonyms: | US8536175, 82 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C29H30Cl2N6O3 | ||
| Mol. Mass. | 581.493 | ||
| SMILES | CCN1CCN(Cc2cnc3c(ccc(C(=O)Nc4cccnc4)c3n2)-c2c(Cl)c(OC)cc(OC)c2Cl)CC1 |(-8.08,-5.33,;-7.31,-4,;-5.78,-4,;-5,-2.67,;-3.47,-2.67,;-2.69,-4,;-1.15,-4,;-.38,-2.67,;1.15,-2.67,;1.93,-1.33,;1.15,,;1.93,1.33,;1.15,2.67,;-.38,2.67,;-1.15,1.33,;-2.69,1.33,;-3.47,2.67,;-3.47,,;-5,,;-5.78,1.33,;-7.31,1.33,;-8.08,,;-7.31,-1.33,;-5.78,-1.33,;-.38,,;-1.15,-1.33,;3.47,1.33,;4.23,,;3.47,-1.33,;5.78,,;6.55,-1.33,;8.09,-1.33,;6.55,1.33,;5.78,2.67,;6.55,4,;5.78,5.33,;4.23,2.67,;3.47,4,;-3.47,-5.33,;-5,-5.33,)| | ||
| Structure | 
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