Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fibroblast growth factor receptor 3 | ||
| Ligand | BDBM102529 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | LanthaScreen TR-FRET Assay | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 1050±n/a nM | ||
| Comments | extracted | ||
| Citation |  Furet, P; Graus Porta, D; Guagnano, V Quinoline carboxamide derivatives as protein tyrosine kinase inhibitors US Patent US8815901 Publication Date 8/26/2014 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fibroblast growth factor receptor 3 | |||
| Name: | Fibroblast growth factor receptor 3 | ||
| Synonyms: | CD_antigen: CD333 | FGFR-3 | FGFR3 | FGFR3_HUMAN | Fibroblast growth factor receptor | Fibroblast growth factor receptor 3 (FGFR3) | JTK4 | ||
| Type: | Protein | ||
| Mol. Mass.: | 87699.57 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P22607 | ||
| Residue: | 806 | ||
| Sequence: |
| ||
| BDBM102529 | |||
| n/a | |||
| Name | BDBM102529 | ||
| Synonyms: | US8536175, 98 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C30H33ClN6O2 | ||
| Mol. Mass. | 545.075 | ||
| SMILES | CCN1CCN(Cc2ccc(NC(=O)c3ccc(-c4c(C)c(OC)cc(C)c4Cl)c4nccnc34)nc2)CC1 |(-8.85,4.67,;-9.62,3.33,;-8.85,2,;-7.31,2,;-6.54,.67,;-7.31,-.67,;-6.54,-2,;-5,-2,;-4.23,-.67,;-2.69,-.67,;-1.92,-2,;-.38,-2,;.39,-.67,;-.38,.67,;1.93,-.67,;2.7,.67,;4.24,.67,;5.01,-.67,;6.55,-.67,;7.32,.67,;6.55,2,;8.86,.67,;9.63,2,;11.17,2,;9.63,-.67,;8.86,-2,;9.63,-3.33,;7.32,-2,;6.55,-3.33,;4.24,-2,;5.01,-3.33,;4.24,-4.67,;2.7,-4.67,;1.93,-3.33,;2.7,-2,;-2.69,-3.33,;-4.23,-3.33,;-8.85,-.67,;-9.62,.67,)| | ||
| Structure | 
| ||