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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fibroblast growth factor receptor 3 | ||
| Ligand | BDBM130083 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | LanthaScreen TR-FRET Assay | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 9±n/a nM | ||
| Comments | extracted | ||
| Citation |  Furet, P; Graus Porta, D; Guagnano, V Quinoline carboxamide derivatives as protein tyrosine kinase inhibitors US Patent US8815901 Publication Date 8/26/2014 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fibroblast growth factor receptor 3 | |||
| Name: | Fibroblast growth factor receptor 3 | ||
| Synonyms: | CD_antigen: CD333 | FGFR-3 | FGFR3 | FGFR3_HUMAN | Fibroblast growth factor receptor | Fibroblast growth factor receptor 3 (FGFR3) | JTK4 | ||
| Type: | Protein | ||
| Mol. Mass.: | 87699.57 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P22607 | ||
| Residue: | 806 | ||
| Sequence: |
| ||
| BDBM130083 | |||
| n/a | |||
| Name | BDBM130083 | ||
| Synonyms: | US8815901, 175 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H23F2N5O3 | ||
| Mol. Mass. | 467.4679 | ||
| SMILES | COc1cc(OC)c(F)c(c1F)-c1ccc(C(=O)Nc2ncc(CN(C)C)[nH]2)c2ncccc12 |(9.64,-2.74,;8.1,-2.74,;7.33,-1.41,;8.1,-.08,;7.33,1.26,;8.1,2.59,;7.33,3.93,;5.79,1.26,;5.02,2.59,;5.02,-.08,;5.79,-1.41,;5.02,-2.74,;3.48,-.08,;2.71,1.26,;1.17,1.26,;.4,-.08,;-1.14,-.08,;-1.91,1.26,;-1.91,-1.41,;-3.44,-1.41,;-4.34,-.16,;-5.81,-.64,;-5.81,-2.18,;-7.14,-2.95,;-8.48,-2.18,;-9.81,-2.95,;-8.48,-.64,;-4.34,-2.65,;1.17,-1.41,;.4,-2.74,;1.17,-4.08,;2.71,-4.08,;3.48,-2.74,;2.71,-1.41,)| | ||
| Structure | 
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