| Reaction Details |
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 | Report a problem with these data |
| Target | Coagulation factor X |
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| Ligand | BDBM7847 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzyme Inhibition Assay |
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| Temperature | 298.15±n/a K |
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| IC50 | 210±n/a nM |
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| Comments | extracted |
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| Citation |  Straub, A; Lampe, T; Pohlmann, J; Röhrig, S; Perzborn, E; Schlemmer, K; Pernerstofer, J Substituted oxazolidinones and their use in the field of blood coagulation US Patent US8822458 Publication Date 9/2/2014 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Coagulation factor X |
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| Name: | Coagulation factor X |
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| Synonyms: | Activated coagulation factor X (FXa) | Activated factor Xa heavy chain | Coagulation factor X precursor | Coagulation factor Xa | F10 | FA10_HUMAN | Factor X heavy chain | Factor X light chain | Factor Xa | Stuart factor | Stuart-Prower factor |
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| Type: | Enzyme |
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| Mol. Mass.: | 54726.60 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 488 |
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| Sequence: | MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEE
TCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKN
CELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERR
KRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQE
CKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGE
AVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGI
VSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSG
GPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPE
VITSSPLK
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| BDBM7847 |
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| n/a |
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| Name | BDBM7847 |
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| Synonyms: | US8822458, 15 |
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| Type | n/a |
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| Emp. Form. | C19H19ClFN3O5S2 |
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| Mol. Mass. | 487.953 |
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| SMILES | Fc1cc(ccc1N1CCS(=O)(=O)CC1)N1C[C@H](CNC(=O)c2ccc(Cl)s2)OC1=O |r| |
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| Structure | 
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