| Reaction Details |
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 | Report a problem with these data |
| Target | Cyclin-dependent kinase 2 |
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| Ligand | BDBM148261 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | IMAP-FPT (Molecular Devices Trade Mark Technology) Endpoint Assay |
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| IC50 | >15000±n/a nM |
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| Citation |  Brain, CT; Sung, MJ; Lagu, B Pyrrolopyrimidine compounds and their uses US Patent US8962630 Publication Date 2/24/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Cyclin-dependent kinase 2 |
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| Name: | Cyclin-dependent kinase 2 |
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| Synonyms: | CDK2 | CDK2-Kinase | CDK2_HUMAN | CDKN2 | Cell division protein kinase 2 | Cyclin-dependent kinase 2 (CDK2) | Protein cereblon/Cyclin-dependent kinase 2 | p33 protein kinase |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 33938.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P24941 |
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| Residue: | 298 |
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| Sequence: | MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY
STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
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| BDBM148261 |
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| n/a |
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| Name | BDBM148261 |
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| Synonyms: | US8962630, 71 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H38N8O2 |
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| Mol. Mass. | 506.643 |
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| SMILES | CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCN(CC(C)(C)O)CC3)nc2n1C1CCCC1 |
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| Structure | 
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