| Reaction Details |
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 | Report a problem with these data |
| Target | C-X-C chemokine receptor type 3 |
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| Ligand | BDBM166560 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Competition Radioligand Binding Assay |
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| IC50 | 3200±n/a nM |
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| Citation |  Bata, I; Buzder-Lantos, P; Vasas, A; Bartane Bodor, V; Ferenczy, G; Tomoskozi, Z; Szeleczky, G; Batori, S; Smrcina, M; Patek, M; Weichsel, A; Thorpe, DS Cycloalkane carboxylic acid derivatives as CXCR3 receptor antagonists US Patent US9073853 Publication Date 7/7/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| C-X-C chemokine receptor type 3 |
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| Name: | C-X-C chemokine receptor type 3 |
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| Synonyms: | AAO92295.1 | C-X-C chemokine receptor type 3 | C-X-C chemokine receptor type 3 (CXCR3) | C-X-C chemokine receptor type 3 (CXCR3A) | CXCR3 | CXCR3A | CXCR3_HUMAN | GPR9 | chemokine (C-X-C motif) receptor 3 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 40665.65 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 368 |
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| Sequence: | MVLEVSDHQVLNDAEVAALLENFSSSYDYGENESDSCCTSPPCPQDFSLNFDRAFLPALY
SLLFLLGLLGNGAVAAVLLSRRTALSSTDTFLLHLAVADTLLVLTLPLWAVDAAVQWVFG
SGLCKVAGALFNINFYAGALLLACISFDRYLNIVHATQLYRRGPPARVTLTCLAVWGLCL
LFALPDFIFLSAHHDERLNATHCQYNFPQVGRTALRVLQLVAGFLLPLLVMAYCYAHILA
VLLVSRGQRRLRAMRLVVVVVVAFALCWTPYHLVVLVDILMDLGALARNCGRESRVDVAK
SVTSGLGYMHCCLNPLLYAFVGVKFRERMWMLLLRLGCPNQRGLQRQPSSSRRDSSWSET
SEASYSGL
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| BDBM166560 |
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| n/a |
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| Name | BDBM166560 |
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| Synonyms: | US9073853, 119 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H31ClN2O6 |
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| Mol. Mass. | 527.009 |
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| SMILES | COc1cc(CN(CC2(CC2)C(O)=O)C2CCc3cc(Cl)ccc23)ccc1OCCN1C(=O)CCC1=O |
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| Structure | 
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