Reaction Details |
| Report a problem with these data |
Target | Complement factor D |
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Ligand | BDBM171002 |
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Substrate/Competitor | n/a |
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Meas. Tech. | In Vitro Assay |
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pH | 7.5±n/a |
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Temperature | 298.15±n/a K |
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IC50 | 7±n/a nM |
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Comments | extracted |
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Citation | Altmann, E; Hommel, U; Lorthiois, EL; Maibaum, JK; Ostermann, N; Quancard, J; Randl, SA; Rogel, O; Simic, O; Vulpetti, A Complement pathway modulators and uses thereof US Patent US9085555 Publication Date 7/21/2015 |
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More Info.: | Get all data from this article, Assay Method |
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Complement factor D |
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Name: | Complement factor D |
Synonyms: | Adipsin | C3 convertase activator | CFAD_HUMAN | CFD | DF | PFD | Properdin factor D |
Type: | Protein |
Mol. Mass.: | 27039.19 |
Organism: | Homo sapiens (Human) |
Description: | P00746 |
Residue: | 253 |
Sequence: | MHSWERLAVLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQW
VLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQL
SEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCN
RRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTR
VASYAAWIDSVLA
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BDBM171002 |
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n/a |
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Name | BDBM171002 |
Synonyms: | US9085555, 432 |
Type | Small organic molecule |
Emp. Form. | C21H20ClFN6O3 |
Mol. Mass. | 458.873 |
SMILES | NC(=O)n1cc(NC(=O)N2NCC[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc12 |r| |
Structure |
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