| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 5 |
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| Ligand | BDBM231697 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | pERK Assay |
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| IC50 | 4.8e+3±n/a nM |
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| Citation |  Bongard, RD; Lepley, M; Thakur, K; Talipov, MR; Nayak, J; Lipinski, RAJ; Bohl, C; Sweeney, N; Ramchandran, R; Rathore, R; Sem, DS Serendipitous discovery of light-induced (In Situ) formation of an Azo-bridged dimeric sulfonated naphthol as a potent PTP1B inhibitor. BMC Biochem18:1-15 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dual specificity protein phosphatase 5 |
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| Name: | Dual specificity protein phosphatase 5 |
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| Synonyms: | DUS5_HUMAN | DUSP5 | Dual-specificity phosphatase 5 phophatase (DUSP5) | VH3 |
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| Type: | Enzyme |
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| Mol. Mass.: | 42058.96 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q16690 |
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| Residue: | 384 |
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| Sequence: | MKVTSLDGRQLRKMLRKEAAARCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRARGGAV
SARYVLPDEAARARLLQEGGGGVAAVVVLDQGSRHWQKLREESAARVVLTSLLACLPAGP
RVYFLKGGYETFYSEYPECCVDVKPISQEKIESERALISQCGKPVVNVSYRPAYDQGGPV
EILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACATHLHYKWIPVEDSHTADISS
HFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMV
SPNFGFMGQLLQYESEILPSTPNPQPPSCQGEAAGSSLIGHLQTLSPDMQGAYCTFPASV
LAPVPTHSTVSELSRSPVATATSC
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| BDBM231697 |
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| n/a |
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| Name | BDBM231697 |
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| Synonyms: | RR601 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H14N2O8S2 |
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| Mol. Mass. | 474.464 |
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| SMILES | Oc1cc(cc2c(cccc12)\N=N\c1cccc2c(O)cc(cc12)S(O)(=O)=O)S(O)(=O)=O |
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| Structure | 
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