| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Taste receptor type 1 member 2/3 |
|---|
| Ligand | BDBM253879 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Immunological Binding Assay |
|---|
| Temperature | 283.15±n/a K |
|---|
| EC50 | 830±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Li, X; Staszewski, L; Xu, H Use of T1R3 venus flytrap region polypeptide to screen for taste modulators US Patent US9459250 Publication Date 10/4/2016 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Taste receptor type 1 member 2/3 |
|---|
| Name: | Taste receptor type 1 member 2/3 |
|---|
| Synonyms: | T1R2/T1R3 | Taste Receptor T1R2/T1R3 |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | n/a |
|---|
| Description: | ASSAY_ID of ChEMBL is 1994278 |
|---|
| Components: | This complex has 2 components. |
|---|
| Component 1 |
| Name: | Taste receptor type 1 member 2 |
|---|
| Synonyms: | GPR71 | T1R2 | TAS1R2 | TR2 | TS1R2_HUMAN | Taste receptor type 1 member 2 (T1R2) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 95182.38 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q8TE23 |
|---|
| Residue: | 839 |
|---|
| Sequence: | MGPRAKTISSLFFLLWVLAEPAENSDFYLPGDYLLGGLFSLHANMKGIVHLNFLQVPMCK
EYEVKVIGYNLMQAMRFAVEEINNDSSLLPGVLLGYEIVDVCYISNNVQPVLYFLAHEDN
LLPIQEDYSNYISRVVAVIGPDNSESVMTVANFLSLFLLPQITYSAISDELRDKVRFPAL
LRTTPSADHHIEAMVQLMLHFRWNWIIVLVSSDTYGRDNGQLLGERVARRDICIAFQETL
PTLQPNQNMTSEERQRLVTIVDKLQQSTARVVVVFSPDLTLYHFFNEVLRQNFTGAVWIA
SESWAIDPVLHNLTELRHLGTFLGITIQSVPIPGFSEFREWGPQAGPPPLSRTSQSYTCN
QECDNCLNATLSFNTILRLSGERVVYSVYSAVYAVAHALHSLLGCDKSTCTKRVVYPWQL
LEEIWKVNFTLLDHQIFFDPQGDVALHLEIVQWQWDRSQNPFQSVASYYPLQRQLKNIQD
ISWHTINNTIPMSMCSKRCQSGQKKKPVGIHVCCFECIDCLPGTFLNHTEDEYECQACPN
NEWSYQSETSCFKRQLVFLEWHEAPTIAVALLAALGFLSTLAILVIFWRHFQTPIVRSAG
GPMCFLMLTLLLVAYMVVPVYVGPPKVSTCLCRQALFPLCFTICISCIAVRSFQIVCAFK
MASRFPRAYSYWVRYQGPYVSMAFITVLKMVIVVIGMLATGLSPTTRTDPDDPKITIVSC
NPNYRNSLLFNTSLDLLLSVVGFSFAYMGKELPTNYNEAKFITLSMTFYFTSSVSLCTFM
SAYSGVLVTIVDLLVTVLNLLAISLGYFGPKCYMILFYPERNTPAYFNSMIQGYTMRRD
|
|
|
|---|
| Component 2 |
| Name: | Taste receptor type 1 member 3 |
|---|
| Synonyms: | T1R3 | TAS1R3 | TR3 | TS1R3_HUMAN | Taste receptor type 1 member 3 (T1R3) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 93393.60 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q7RTX0 |
|---|
| Residue: | 852 |
|---|
| Sequence: | MLGPAVLGLSLWALLHPGTGAPLCLSQQLRMKGDYVLGGLFPLGEAEEAGLRSRTRPSSP
VCTRFSSNGLLWALAMKMAVEEINNKSDLLPGLRLGYDLFDTCSEPVVAMKPSLMFLAKA
GSRDIAAYCNYTQYQPRVLAVIGPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARETF
PSFFRTVPSDRVQLTAAAELLQEFGWNWVAALGSDDEYGRQGLSIFSALAAARGICIAHE
GLVPLPRADDSRLGKVQDVLHQVNQSSVQVVLLFASVHAAHALFNYSISSRLSPKVWVAS
EAWLTSDLVMGLPGMAQMGTVLGFLQRGAQLHEFPQYVKTHLALATDPAFCSALGEREQG
LEEDVVGQRCPQCDCITLQNVSAGLNHHQTFSVYAAVYSVAQALHNTLQCNASGCPAQDP
VKPWQLLENMYNLTFHVGGLPLRFDSSGNVDMEYDLKLWVWQGSVPRLHDVGRFNGSLRT
ERLKIRWHTSDNQKPVSRCSRQCQEGQVRRVKGFHSCCYDCVDCEAGSYRQNPDDIACTF
CGQDEWSPERSTRCFRRRSRFLAWGEPAVLLLLLLLSLALGLVLAALGLFVHHRDSPLVQ
ASGGPLACFGLVCLGLVCLSVLLFPGQPSPARCLAQQPLSHLPLTGCLSTLFLQAAEIFV
ESELPLSWADRLSGCLRGPWAWLVVLLAMLVEVALCTWYLVAFPPEVVTDWHMLPTEALV
HCRTRSWVSFGLAHATNATLAFLCFLGTFLVRSQPGCYNRARGLTFAMLAYFITWVSFVP
LLANVQVVLRPAVQMGALLLCVLGILAAFHLPRCYLLMRQPGLNTPEFFLGGGPGDAQGQ
NDGNTGNQGKHE
|
|
|
|---|
| BDBM253879 |
|---|
| n/a |
|---|
| Name | BDBM253879 |
|---|
| Synonyms: | US9459250, E84 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H10Cl2FNO2 |
|---|
| Mol. Mass. | 314.139 |
|---|
| SMILES | COc1c(Cl)ccc(Cl)c1C(=O)Nc1ccccc1F |
|---|
| Structure | 
|
|---|
Search and Browse
