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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Amine oxidase [flavin-containing] B | ||
| Ligand | BDBM254593 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Fluorescence-Based (Inhibitor)-Screening Assay | ||
| pH | 7.5±n/a | ||
| Temperature | 310.15±n/a K | ||
| IC50 | 65010±n/a nM | ||
| Comments | extracted | ||
| Citation |  Ortega Muñoz, A; Fyfe, MC; Martinell Pedemonte, M; Estiarte Martínez, M; Valls Vidal, N; Kurz, G; Castro Palomino Laria, JC (Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors US Patent US9469597 Publication Date 10/18/2016 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Amine oxidase [flavin-containing] B | |||
| Name: | Amine oxidase [flavin-containing] B | ||
| Synonyms: | AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB) | ||
| Type: | Protein | ||
| Mol. Mass.: | 58768.76 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P27338 | ||
| Residue: | 520 | ||
| Sequence: |
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| BDBM254593 | |||
| n/a | |||
| Name | BDBM254593 | ||
| Synonyms: | US9469597, 52 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H35N5O2S | ||
| Mol. Mass. | 469.643 | ||
| SMILES | NC1CCC(CC1)N[C@H]1C[C@@H]1c1ccc(cc1)-c1cccc(NS(=O)(=O)N2CCNCC2)c1 |r,wU:10.12,wD:8.8,(11.44,3.85,;10.11,3.08,;10.11,1.54,;8.77,.77,;7.44,1.54,;7.44,3.08,;8.77,3.85,;6.1,.77,;4.77,1.54,;4,2.87,;3.23,1.54,;1.9,.77,;.56,1.54,;-.77,.77,;-.77,-.77,;.56,-1.54,;1.9,-.77,;-2.1,-1.54,;-2.1,-3.08,;-3.44,-3.85,;-4.77,-3.08,;-4.77,-1.54,;-6.1,-.77,;-7.44,-1.54,;-6.67,-2.87,;-8.21,-2.87,;-8.77,-.77,;-8.77,.77,;-10.11,1.54,;-11.44,.77,;-11.44,-.77,;-10.11,-1.54,;-3.44,-.77,)| | ||
| Structure | 
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