| Reaction Details |
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 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor delta |
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| Ligand | BDBM412339 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luciferase Assay |
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| EC50 | 0.100±n/a nM |
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| Citation |  Downes, M; Evans, RM; Kluge, A; Lagu, B; Miura, M; Panigrahi, SK; Patane, M; Samajdar, S; Senaiar, R; Takahashi, T PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof US Patent US10399958 Publication Date 9/3/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Peroxisome proliferator-activated receptor delta |
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| Name: | Peroxisome proliferator-activated receptor delta |
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| Synonyms: | NR1C2 | NUC1 | NUCI | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR delta | PPAR-beta | PPARB | PPARD | PPARD_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor beta | Peroxisome proliferator-activated receptor delta |
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| Type: | Enzyme |
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| Mol. Mass.: | 49910.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q03181 |
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| Residue: | 441 |
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| Sequence: | MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQM
GCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKK
NRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSK
HIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKE
ISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNK
DGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGD
RPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRI
KKTETETSLHPLLQEIYKDMY
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| BDBM412339 |
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| n/a |
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| Name | BDBM412339 |
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| Synonyms: | US10399958, Compound 2d |
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| Type | Small organic molecule |
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| Emp. Form. | C25H27F3N2O3 |
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| Mol. Mass. | 460.4887 |
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| SMILES | CC(CCCOc1ccccc1Cn1c(C)cnc1-c1ccc(cc1)C(F)(F)F)CC(O)=O |
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| Structure | 
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