Reaction Details | |||
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Target | Cyclin-dependent kinase 9 | ||
Ligand | BDBM454573 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Kinase Assay (ATP Concentration at Km) | ||
IC50 | <3.00±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Cyclin-dependent kinase 9 | |||
Name: | Cyclin-dependent kinase 9 | ||
Synonyms: | C-2K | CDC2L4 | CDK9 | CDK9_HUMAN | Cell division cycle 2-like protein kinase 4 | Cell division protein kinase 9 | Cyclin-Dependent Kinase 9 (CDK9) | Cyclin-dependent kinase 9 (CDK9) | Serine/threonine-protein kinase PITALRE | TAK | Tat-associated kinase complex catalytic subunit | ||
Type: | Enzyme Subunit | ||
Mol. Mass.: | 42789.13 | ||
Organism: | Homo sapiens (Human) | ||
Description: | n/a | ||
Residue: | 372 | ||
Sequence: |
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BDBM454573 | |||
n/a | |||
Name | BDBM454573 | ||
Synonyms: | US10717746, Example 53 | ||
Type | Small organic molecule | ||
Emp. Form. | C25H32ClN5O3 | ||
Mol. Mass. | 486.006 | ||
SMILES | CC1(C)Cc2c(cnn2C1)-c1cc(NC(=O)[C@H]2CCC[C@H](C2)NC(=O)[C@@H]2C[C@H](O)C2)ncc1Cl |r,wD:16.17,20.24,25.27,27.30,(-1.68,4.97,;-3.02,4.2,;-1.68,3.43,;-3.49,2.73,;-5.03,2.73,;-6.28,1.83,;-7.52,2.73,;-7.05,4.2,;-5.51,4.2,;-4.26,5.1,;-6.28,.29,;-4.94,-.48,;-4.94,-2.02,;-3.61,-2.79,;-2.28,-2.02,;-2.28,-.48,;-.94,-2.79,;-.94,-4.33,;.39,-5.1,;1.72,-4.33,;1.72,-2.79,;.39,-2.02,;3.06,-2.02,;4.39,-2.79,;4.39,-4.33,;5.73,-2.02,;6.12,-.53,;7.61,-.93,;8.95,-.16,;7.21,-2.42,;-6.28,-2.79,;-7.61,-2.02,;-7.61,-.48,;-8.95,.29,)| | ||
Structure | ![]() |