| Reaction Details |
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 | Report a problem with these data |
| Target | Pantetheinase |
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| Ligand | BDBM480918 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzyme Assay |
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| IC50 | 0.349±n/a nM |
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| Citation |  Casimiro-Garcia, A; Strohbach, JW; Hepworth, D; Lovering, FE; Choi, C; Allais, CP; Wright, SW Pyrimidine carboxamides as inhibitors of Vanin-1 enzyme US Patent US10906888 Publication Date 2/2/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| Pantetheinase |
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| Name: | Pantetheinase |
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| Synonyms: | Pantetheine hydrolase | Tiff66 | VNN1 | VNN1_HUMAN | Vanin-1 | Vascular non-inflammatory molecule 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 57002.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O95497 |
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| Residue: | 513 |
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| Sequence: | MTTQLPAYVAILLFYVSRASCQDTFTAAVYEHAAILPNATLTPVSREEALALMNRNLDIL
EGAITSAADQGAHIIVTPEDAIYGWNFNRDSLYPYLEDIPDPEVNWIPCNNRNRFGQTPV
QERLSCLAKNNSIYVVANIGDKKPCDTSDPQCPPDGRYQYNTDVVFDSQGKLVARYHKQN
LFMGENQFNVPKEPEIVTFNTTFGSFGIFTCFDILFHDPAVTLVKDFHVDTIVFPTAWMN
VLPHLSAVEFHSAWAMGMRVNFLASNIHYPSKKMTGSGIYAPNSSRAFHYDMKTEEGKLL
LSQLDSHPSHSAVVNWTSYASSIEALSSGNKEFKGTVFFDEFTFVKLTGVAGNYTVCQKD
LCCHLSYKMSENIPNEVYALGAFDGLHTVEGRYYLQICTLLKCKTTNLNTCGDSAETAST
RFEMFSLSGTFGTQYVFPEVLLSENQLAPGEFQVSTDGRLFSLKPTSGPVLTVTLFGRLY
EKDWASNASSGLTAQARIIMLIVIAPIVCSLSW
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| BDBM480918 |
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| n/a |
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| Name | BDBM480918 |
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| Synonyms: | US10906888, Example 132 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H24N6O3 |
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| Mol. Mass. | 396.443 |
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| SMILES | O=C(N1CCC2(C1)CCOCC2)c1cnc(NC2(COC2)c2cnccn2)nc1 |
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| Structure | 
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