Reaction Details | |||
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Target | Non-receptor tyrosine-protein kinase TYK2 [580-1182] | ||
Ligand | BDBM505108 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Enzymatic Inhibition Assay | ||
IC50 | 1.50±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Non-receptor tyrosine-protein kinase TYK2 [580-1182] | |||
Name: | Non-receptor tyrosine-protein kinase TYK2 [580-1182] | ||
Synonyms: | TYK2 | TYK2 (aa 580-1182) | TYK2_HUMAN | ||
Type: | n/a | ||
Mol. Mass.: | 68754.63 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P29597[580-1182] | ||
Residue: | 608 | ||
Sequence: |
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BDBM505108 | |||
n/a | |||
Name | BDBM505108 | ||
Synonyms: | US11066406, Ex. 2 | ||
Type | Small organic molecule | ||
Emp. Form. | C19H19N7 | ||
Mol. Mass. | 345.4011 | ||
SMILES | N#CCC1CCC(CC1)n1c(nc2cnc3[nH]ccc3c12)-c1c[nH]cn1 |(5.02,-6.52,;3.87,-5.49,;2.73,-4.46,;3.05,-2.96,;4.51,-2.48,;4.83,-.98,;3.69,.06,;2.23,-.42,;1.91,-1.93,;4.01,1.56,;5.42,2.19,;5.26,3.72,;3.75,4.04,;2.98,5.37,;1.44,5.37,;.67,4.04,;-.84,3.72,;-1,2.19,;.41,1.56,;1.44,2.71,;2.98,2.71,;6.75,1.42,;8.16,2.04,;9.19,.9,;8.42,-.43,;6.91,-.11,)| | ||
Structure | ![]() |