| Reaction Details |
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 | Report a problem with these data |
| Target | Bromodomain-containing protein 4 [44-168] |
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| Ligand | BDBM209483 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | AlphaScreen Assay |
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| IC50 | 20.0±n/a nM |
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| Citation |  Engelhardt, H; Gianni, D; Smethurst, C Triazolopyrazine US Patent US11077107 Publication Date 8/3/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| Bromodomain-containing protein 4 [44-168] |
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| Name: | Bromodomain-containing protein 4 [44-168] |
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| Synonyms: | BET bromodomain 4(1) (BRD4(1)) | BRD4 | BRD4-BD1 protein (aa 44-168) | BRD4_HUMAN | Bromodomain protein 4 (BRD4-BD1) | Bromodomain-containing protein 4 (BRD4-BD1) | Bromodomain-containing protein 4 (BRD4) (aa 44-168) | Bromodomain-containing protein 4 (BRD4-BD1) | Bromodomain-containing protein 4 bromodomain 1 (BRD4-BD1) | HUNK1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 14866.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | aa (44-168) |
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| Residue: | 125 |
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| Sequence: | NPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKT
PMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINE
LPTEE
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| BDBM209483 |
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| n/a |
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| Name | BDBM209483 |
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| Synonyms: | US10328074, Example III-24 | US11077107, Example III-24 | US9266891, III-24 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H28N10O2 |
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| Mol. Mass. | 512.5663 |
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| SMILES | Cc1nnc2c(N[C@@H]3CCOC3)nc(cn12)-c1nc2cnc(cc2n1Cc1ccccn1)N1CCOCC1 |r| |
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| Structure | 
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