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TargetBromodomain-containing protein 4 [44-168]
LigandBDBM209497
Substrate/Competitorn/a
Meas. Tech.AlphaScreen Assay
IC50 17.0±n/a nM
Citation Engelhardt, H; Gianni, D; Smethurst, C Triazolopyrazine US Patent US11077107 Publication Date 8/3/2021
More Info.:Get all data from this article,  Assay Method
 
Bromodomain-containing protein 4 [44-168]
Name:Bromodomain-containing protein 4 [44-168]
Synonyms:BET bromodomain 4(1) (BRD4(1)) | BRD4 | BRD4-BD1 protein (aa 44-168) | BRD4_HUMAN | Bromodomain protein 4 (BRD4-BD1) | Bromodomain-containing protein 4 (BRD4-BD1) | Bromodomain-containing protein 4 (BRD4) (aa 44-168) | Bromodomain-containing protein 4 (BRD4-BD1) | Bromodomain-containing protein 4 bromodomain 1 (BRD4-BD1) | HUNK1
Type:Enzyme Catalytic Domain
Mol. Mass.:14866.49
Organism:Homo sapiens (Human)
Description:aa (44-168)
Residue:125
Sequence:
NPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKT
PMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINE
LPTEE
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  Blast E-value cutoff:
BDBM209497
n/a
NameBDBM209497
Synonyms:US10328074, Example III-38 | US11077107, Example III-38 | US9266891, III-38
TypeSmall organic molecule
Emp. Form.C26H30N10O
Mol. Mass.498.5828
SMILESCC(C)Nc1nc(cn2c(C)nnc12)-c1nc2cnc(cc2n1Cc1cccc(C)n1)N1CCOCC1
Structure
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