| Reaction Details |
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 | Report a problem with these data |
| Target | Probable G-protein coupled receptor 139 |
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| Ligand | BDBM263457 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Radioligand Assay |
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| Ki | 110±n/a nM |
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| Citation |  Hitchcock, S; Lam, B; Monenschein, H; Reichard, H 4-oxo-3,4-dihydro-1,2,3-benzotriazine modulators of GPR139 US Patent US11173161 Publication Date 11/16/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| Probable G-protein coupled receptor 139 |
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| Name: | Probable G-protein coupled receptor 139 |
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| Synonyms: | G(q)-coupled orphan receptor GPRg1 | G-protein coupled receptor 139 | G-protein-coupled receptor PGR3 | GP139_HUMAN | GPR139 | GPRG1 | GPRG1 | PGR3 | Probable G-protein coupled receptor 139 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40700.34 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_109920 |
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| Residue: | 353 |
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| Sequence: | MEHTHAHLAANSSLSWWSPGSACGLGFVPVVYYSLLLCLGLPANILTVIILSQLVARRQK
SSYNYLLALAAADILVLFFIVFVDFLLEDFILNMQMPQVPDKIIEVLEFSSIHTSIWITV
PLTIDRYIAVCHPLKYHTVSYPARTRKVIVSVYITCFLTSIPYYWWPNIWTEDYISTSVH
HVLIWIHCFTVYLVPCSIFFILNSIIVYKLRRKSNFRLRGYSTGKTTAILFTITSIFATL
WAPRIIMILYHLYGAPIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFRTMAAATL
KAFFKCQKQPVQFYTNHNFSITSSPWISPANSHCIKMLVYQYDKNGKPIKVSP
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| BDBM263457 |
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| n/a |
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| Name | BDBM263457 |
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| Synonyms: | (s)-2-(8-chloro-4-oxobenzo[d][1,2,3]triazin-3(4h)-yl)-n-(1-p-tolylethyl)acetamide | US10561662, Example 22 | US11173161, EX 22 | US9556130, test 22 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H17ClN4O2 |
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| Mol. Mass. | 356.806 |
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| SMILES | C[C@H](NC(=O)Cn1nnc2c(Cl)cccc2c1=O)c1ccc(C)cc1 |r| |
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| Structure | 
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