| Reaction Details |
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 | Report a problem with these data |
| Target | C-C chemokine receptor type 6 |
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| Ligand | BDBM531141 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Biological Assay |
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| IC50 | 37.0±n/a nM |
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| Citation |  Hein, CD; Duong, TT; Sinha, S; Li, L; Nguyen, JH; Old, DW; Burk, R; Viswanath, V; Rao, S; Donello, JE 3,4-disubstituted 3-cyclobutene-1,2-diones and use thereof US Patent US11208377 Publication Date 12/28/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| C-C chemokine receptor type 6 |
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| Name: | C-C chemokine receptor type 6 |
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| Synonyms: | C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22 |
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| Type: | Enzyme |
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| Mol. Mass.: | 42510.84 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P51684 |
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| Residue: | 374 |
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| Sequence: | MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFG
LLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKL
LKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISS
STFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKT
LVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTV
TEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQT
SETADNDNASSFTM
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| BDBM531141 |
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| n/a |
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| Name | BDBM531141 |
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| Synonyms: | 6-chloro-3-((2-((2,2-dimethylpentan-3-yl)amino)-3,4-dioxocyclobut-1-en-1-yl)amino)-2-hydroxy-N,N-dimethylbenzenesulfonamide | US11208377, Compound 45 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H26ClN3O5S |
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| Mol. Mass. | 443.945 |
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| SMILES | CCC(Nc1c(Nc2ccc(Cl)c(c2O)S(=O)(=O)N(C)C)c(=O)c1=O)C(C)(C)C |
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| Structure | 
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