| Reaction Details |
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 | Report a problem with these data |
| Target | CAM kinase, CDPK family TgCDPK1 |
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| Ligand | BDBM50249997 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Expression and Purification of Active Kinases |
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| IC50 | 8.94±n/a nM |
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| Citation |  Rutaganira, F; Shokat, KM; Sibley, LD; Janetka, JW Compositions and methods for treating parasitic diseases US Patent US11208411 Publication Date 12/28/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| CAM kinase, CDPK family TgCDPK1 |
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| Name: | CAM kinase, CDPK family TgCDPK1 |
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| Synonyms: | TgCDPK1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 57248.42 |
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| Organism: | Toxoplasma gondii (strain ATCC 50861 / VEG) |
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| Description: | n/a |
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| Residue: | 507 |
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| Sequence: | MGQQESTLGGAAGEPRSRGHAAGTSGGPGDHLHATPGMFVQHSTAIFSDRYKGQRVLGKG
SFGEVILCKDKITGQECAVKVISKRQVKQKTDKESLLREVQLLKQLDHPNIMKLYEFFED
KGYFYLVGEVYTGGELFDEIISRKRFSEVDAARIIRQVLSGITYMHKNKIVHRDLKPENL
LLESKSKDANIRIIDFGLSTHFEASKKMKDKIGTAYYIAPEVLHGTYDEKCDVWSTGVIL
YILLSGCPPFNGANEYDILKKVEKGKYTFELPQWKKVSESAKDLIRKMLTYVPSMRISAR
DALDHEWIQTYTKEQISVDVPSLDNAILNIRQFQGTQKLAQAALLYMGSKLTSQDETKEL
TAIFHKMDKNGDGQLDRAELIEGYKELMRMKGQDASMLDASAVEHEVDQVLDAVDFDKNG
YIEYSEFVTVAMDRKTLLSRERLERAFRMFDSDNSGKISSTELATIFGVSDVDSETWKSV
LSEVDKNNDGEVDFDEFQQMLLKLCGN
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| BDBM50249997 |
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| n/a |
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| Name | BDBM50249997 |
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| Synonyms: | CHEMBL4078124 | US11208411, Compound GXJ230 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H19N5O2 |
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| Mol. Mass. | 313.3544 |
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| SMILES | COc1cccc(Oc2nn(c3ncnc(N)c23)C(C)(C)C)c1 |
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| Structure | 
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