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TargetLow molecular weight phosphotyrosine protein phosphatase
LigandBDBM533148
Substrate/Competitorn/a
Meas. Tech.LMPTP Primary Screening Protocol
IC50 500±n/a nM
Citation Bottini, NZou, JGanji, SRStanford, SPinkerton, AChung, TDHedrick, MArdecky, R Inhibitors of low molecular weight protein tyrosine phosphatase and uses thereof US Patent US11220486 Publication Date 1/11/2022
More Info.:Get all data from this article,  Assay Method
 
Low molecular weight phosphotyrosine protein phosphatase
Name:Low molecular weight phosphotyrosine protein phosphatase
Synonyms:3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:n/a
Mol. Mass.:18042.81
Organism:Homo sapiens (Human)
Description:P24666
Residue:158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRG
QSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSY
DPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
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BDBM533148
n/a
NameBDBM533148
Synonyms:(2-benzo[b]thiophen-6-yl(4-quinolyl))(3- piperidylpropyl)amine | US10626094, Example I257 | US11220486, Compound I257 | US11220486, Compound I78
TypeSmall organic molecule
Emp. Form.C25H27N3S
Mol. Mass.401.567
SMILESC(CNc1cc(nc2ccccc12)-c1ccc2ccsc2c1)CC1CCCNC1
Structure
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