| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Atypical chemokine receptor 3 |
|---|
| Ligand | BDBM549640 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | In Vitro Assay |
|---|
| IC50 | 1.000±n/a nM |
|---|
| Citation |  Aissaoui, H; Guerry, P; Lehembre, F; Pothier, J; Pouzol, L; Richard-Bildstein, S; Yuan, S Piperidine CXCR7 receptor modulators US Patent US11306078 Publication Date 4/19/2022 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Atypical chemokine receptor 3 |
|---|
| Name: | Atypical chemokine receptor 3 |
|---|
| Synonyms: | ACKR3 | ACKR3_HUMAN | C-X-C chemokine receptor type 7 | C-X-C chemokine receptor type 7 (CXCR7) | CMKOR1 | CXC-R7 | CXCR-7 | CXCR7 | Chemokine orphan receptor 1 | G-protein coupled receptor 159 | G-protein coupled receptor RDC1 homolog | GPR159 | RDC-1 | RDC1 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 41498.84 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P25106 |
|---|
| Residue: | 362 |
|---|
| Sequence: | MDLHLFDYSEPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMI
ANSVVVWVNIQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVT
HLIFSINLFGSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDT
YYLKTVTSASNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAIS
ASSDQEKHSSRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVT
QCLSLVHCCVNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQS
TK
|
|
|
|---|
| BDBM549640 |
|---|
| n/a |
|---|
| Name | BDBM549640 |
|---|
| Synonyms: | US11306078, Example 1.057 | rac-(3R*,4R*)-1-Cyclohexyl-4-{[5-(2,4-difluoro-phenyl)-isoxazole-3- carbonyl]-amino}-piperidine-3-carboxylic acid [2-(2-methoxy-phenyl)- ethyl]-amide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C31H36F2N4O4 |
|---|
| Mol. Mass. | 566.6387 |
|---|
| SMILES | COc1ccccc1CCNC(=O)[C@@H]1CN(CC[C@H]1NC(=O)c1cc(on1)-c1ccc(F)cc1F)C1CCCCC1 |
|---|
| Structure | 
|
|---|
Search and Browse
