| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Protein mono-ADP-ribosyltransferase PARP6 |
|---|
| Ligand | BDBM553962 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Fluorescence Anisotropy Binding Assay |
|---|
| IC50 | >100000±n/a nM |
|---|
| Citation |  Johannes, JW; Hande, SM; Degorce, SL; Packer, MJ Chemical compounds US Patent US11325906 Publication Date 5/10/2022 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Protein mono-ADP-ribosyltransferase PARP6 |
|---|
| Name: | Protein mono-ADP-ribosyltransferase PARP6 |
|---|
| Synonyms: | ADP-ribosyltransferase diphtheria toxin-like 17 | ARTD17 | PARP-6 | PARP6 | PARP6_HUMAN | Poly [ADP-ribose] polymerase 6 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 71130.07 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_107589 |
|---|
| Residue: | 630 |
|---|
| Sequence: | MDIKGQFWNDDDSEGDNESEEFLYGVQGSCAADLYRHPQLDADIEAVKEIYSENSVSIRE
YGTIDDVDIDLHINISFLDEEVSTAWKVLRTEPIVLRLRFSLSQYLDGPEPSIEVFQPSN
KEGFGLGLQLKKILGMFTSQQWKHLSNDFLKTQQEKRHSWFKASGTIKKFRAGLSIFSPI
PKSPSFPIIQDSMLKGKLGVPELRVGRLMNRSISCTMKNPKVEVFGYPPSPQAGLLCPQH
VGLPPPARTSPLVSGHCKNIPTLEYGFLVQIMKYAEQRIPTLNEYCVVCDEQHVFQNGSM
LKPAVCTRELCVFSFYTLGVMSGAAEEVATGAEVVDLLVAMCRAALESPRKSIIFEPYPS
VVDPTDPKTLAFNPKKKNYERLQKALDSVMSIREMTQGSYLEIKKQMDKLDPLAHPLLQW
IISSNRSHIVKLPLSRLKFMHTSHQFLLLSSPPAKEARFRTAKKLYGSTFAFHGSHIENW
HSILRNGLVNASYTKLQLHGAAYGKGIYLSPISSISFGYSGMGKGQHRMPSKDELVQRYN
RMNTIPQTRSIQSRFLQSRNLNCIALCEVITSKDLQKHGNIWVCPVSDHVCTRFFFVYED
GQVGDANINTQDPKIQKEIMRVIGTQVYTN
|
|
|
|---|
| BDBM553962 |
|---|
| n/a |
|---|
| Name | BDBM553962 |
|---|
| Synonyms: | US11325906, Example 25 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H25FN6O2 |
|---|
| Mol. Mass. | 424.4713 |
|---|
| SMILES | CNC(=O)c1ccc(cn1)N1CCN(Cc2ccc3nc(CCF)c(=O)[nH]c3c2)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
