Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Nociceptin receptor | ||
| Ligand | BDBM558083 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Cell-Based NOP Assay | ||
| Ki | >1000±n/a nM | ||
| Citation |  Thompson, JB; Bookser, BC; Burley, S; Garcia-Reynaga, P; Hudson, A; Peters, M; Pratt, B; Thompson, A; Tran, J; Valdez, L Substituted cyclohexyl compounds as NOP inhibiiors US Patent US11365191 Publication Date 6/21/2022 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Nociceptin receptor | |||
| Name: | Nociceptin receptor | ||
| Synonyms: | KOR-3 | Kappa-type 3 opioid receptor | Mu-type opioid receptor (Mu) | NOP | Nociceptin Receptor (ORL1 Receptor) | Nociceptin receptor (NOP) | Nociceptin receptor (ORL-1) | Nociceptin receptor (ORL1) | Nociceptin/Orphanin FQ, NOP receptor | OOR | OPIATE ORL-1 | OPRL1 | OPRL1 protein | OPRX_HUMAN | ORL1 | ORL1 receptor | Opioid receptor like-1 | Orphanin FQ receptor | Orphanin FQ receptor (ORL1) | P41146 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 40702.87 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P41146 | ||
| Residue: | 370 | ||
| Sequence: |
| ||
| BDBM558083 | |||
| n/a | |||
| Name | BDBM558083 | ||
| Synonyms: | US11365191, Example 123 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H31N3O | ||
| Mol. Mass. | 329.4796 | ||
| SMILES | Cc1cnccc1C1CCC(CCNC2(CCCC2)C(N)=O)CC1 |(-5.61,-.87,;-5.61,.67,;-6.94,1.44,;-6.94,2.98,;-5.61,3.75,;-4.28,2.98,;-4.28,1.44,;-2.94,.67,;-2.94,-.87,;-1.61,-1.64,;-.27,-.87,;1.06,-1.64,;2.39,-.87,;3.73,-1.64,;5.06,-.87,;6.59,-.74,;6.94,.76,;5.62,1.55,;4.46,.55,;5.06,-2.41,;6.39,-3.18,;4.29,-3.75,;-.27,.67,;-1.61,1.44,)| | ||
| Structure | 
| ||