| Reaction Details |
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 | Report a problem with these data |
| Target | Vasopressin V1b receptor |
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| Ligand | BDBM175039 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Binding Assay |
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| pH | 7.4±n/a |
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| Temperature | 298.15±n/a K |
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| Ki | <1.00±n/a nM |
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| Comments | extracted |
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| Citation |  Geneste, H; Hornberger, W; Jantos, K; Kling, A; Van Gaalen, M Oxindole compounds carrying a nitrogen-bound spiro substituent and use thereof for treating vasopressin-related diseases US Patent US9688678 Publication Date 6/27/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Vasopressin V1b receptor |
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| Name: | Vasopressin V1b receptor |
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| Synonyms: | AVPR V1b | AVPR V3 | AVPR1B | AVPR3 | Antidiuretic hormone receptor 1b | V1BR_HUMAN | V1bR | VASOPRESSIN V1B | VPR3 | Vasopressin V1b receptor | Vasopressin V1b receptor (V1b) | Vasopressin V3 | Vasopressin V3 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 46985.01 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P47901 |
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| Residue: | 424 |
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| Sequence: | MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNLAVLLTLG
QLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFA
STYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQG
SGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVG
GGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFFSV
QMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHLACCGGPQ
PRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRPRPEESPRDLELADGEGTAE
TIIF
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| BDBM175039 |
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| n/a |
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| Name | BDBM175039 |
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| Synonyms: | US9688678, 11 (+)-3-(2-ethoxy-5-methoxyphenyl)-1-((5-methoxypyridin-2-yl)sulfonyl)-3-(6-(1-(oxetan-3-yl)piperidin-4-yl)-2,6-diazaspiro[3.3]heptan-2-yl)-2-oxoindoline-5-carbonitrile |
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| Type | Small organic molecule |
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| Emp. Form. | C37H44N6O7S |
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| Mol. Mass. | 716.846 |
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| SMILES | CCOc1ccc(OC)c(c1)C1(C2C=C(C=CC2N(C1=O)S(=O)(=O)c1ccc(OC)cn1)C#N)N1CC2(CN(C2)C2CCN(CC2)C2COC2)C1 |c:14,16| |
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| Structure | 
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