| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Apoptosis regulator Bcl-2 |
|---|
| Ligand | BDBM567660 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Bcl-2/Bcl-X TR-FRET Assay |
|---|
| IC50 | 0.032±n/a nM |
|---|
| Citation |  Guo, Y; Xue, H; Wang, Z; Sun, H Bcl-2 inhibitors US Patent US11420968 Publication Date 8/23/2022 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Apoptosis regulator Bcl-2 |
|---|
| Name: | Apoptosis regulator Bcl-2 |
|---|
| Synonyms: | Apoptosis regulator Bcl-2 Protein | B-cell lymphoma 2 protein (Bcl-2) | BCL-2 | BCL2 | BCL2_HUMAN | Bcl-2 Protein |
|---|
| Type: | Homodimer or heterodimer |
|---|
| Mol. Mass.: | 26269.11 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P10415 |
|---|
| Residue: | 239 |
|---|
| Sequence: | MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPA
ASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH
LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY
LNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK
|
|
|
|---|
| BDBM567660 |
|---|
| n/a |
|---|
| Name | BDBM567660 |
|---|
| Synonyms: | US11420968, Example F22 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C47H52FN7O7S |
|---|
| Mol. Mass. | 878.022 |
|---|
| SMILES | [O-][N+](=O)c1cc(ccc1NCC1(F)CCOCC1)S(=O)(=O)NC(=O)c1ccc(cc1Oc1cnc2[nH]ccc2c1)N1CCC2(CC(C2)N2CCC[C@H]2c2ccccc2C2CC2)CC1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
