| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
|---|
| Ligand | BDBM497384 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Pharmacological Activity |
|---|
| Ki | 17.3±n/a nM |
|---|
| Citation |  Godek, DM; Howard, HR; Stewart, AM Cycloalkyl-diamines for the treatment of inflammation US Patent US11426411 Publication Date 8/30/2022 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sigma non-opioid intracellular receptor 1 |
|---|
| Name: | Sigma non-opioid intracellular receptor 1 |
|---|
| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 25124.85 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q99720 |
|---|
| Residue: | 223 |
|---|
| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
|
|
|
|---|
| BDBM497384 |
|---|
| n/a |
|---|
| Name | BDBM497384 |
|---|
| Synonyms: | US11007200, Example 2a | US11426411, Example 2a |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H32ClN3 |
|---|
| Mol. Mass. | 349.941 |
|---|
| SMILES | CN[C@@]1(CCCC[C@@H]1NCCCN1CCCC1)c1ccccc1Cl |
|---|
| Structure | 
|
|---|
Search and Browse
