| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
|---|
| Ligand | BDBM570527 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Receptor Selection and Amplification (R-SAT) Assays |
|---|
| Ki | 0.251±n/a nM |
|---|
| Citation |  Burstein, ES; Olsson, R; Jansson, KE; Sköld, NP; Wahlström, LY; Borgström, BG; Von Wachenfeldt, H; Bergner, MG Compounds, salts thereof and methods for treatment of diseases US Patent US11440884 Publication Date 9/13/2022 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 2A |
|---|
| Name: | 5-hydroxytryptamine receptor 2A |
|---|
| Synonyms: | 5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_HUMAN | HTR2 | HTR2A | Serotonin receptor 2A |
|---|
| Type: | undefined |
|---|
| Mol. Mass.: | 52607.65 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P28223 |
|---|
| Residue: | 471 |
|---|
| Sequence: | MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGC
LSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYK
SSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
|
|
|
|---|
| BDBM570527 |
|---|
| n/a |
|---|
| Name | BDBM570527 |
|---|
| Synonyms: | US11440884, Example 5a | [4-(2-methylpropoxy)phenyl]methyl N-[(4-fluorophenyl)methyl]-N-[(3R,4S)-3-fluoropiperidin-4-yl]carbamate (5a) |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H30F2N2O3 |
|---|
| Mol. Mass. | 432.5034 |
|---|
| SMILES | CC(C)COc1ccc(COC(=O)N(Cc2ccc(F)cc2)[C@H]2CCNC[C@H]2F)cc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
